Methanobrevibacter smithii is highly prevalent in the human gut. Lower counts have been associated with obesity while higher amounts have been associated with anorexia.
References:
Obesity-associated gut microbiota is enriched in Lactobacillus reuteri and depleted in Bifidobacterium animalis and Methanobrevibacter smithii. [L]
- Lower counts of Methanobrevibacter species reported in human obesity
- Reduced levels linked with IBS-D (Irritable Bowel Syndrome with diarrhea)
- Some studies have reported lower counts in IBD (Inflammatory Bowel Disease) conversely, other have reported Increased abundance
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- Abundance associated with higher bacterial gene richness in the gut
- Higher amounts reported in anorexia, in contrast, one study confirmed a positive association with increased BMI and body fat in methanogen-colonized populations
- Higher levels linked to IBS-C (Irritable Bowel Syndrome with Constipation)
- Methanogens found higher in people with colon cancer, colonic polyposis, ulcerative colitis and diverticular disease (sigmoidoscopy enema samples)
- Some studies have reported lower counts in IBD conversely, other have reported Increased abundance
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Acetate, Akkermansia muciniphila, alpha haemolytic Streptococcus, Anaerotruncus colihominis, Anaerotruncus colihominis/massiliensis, Ancylostoma/Necator (Hookworm), Ascaris lumbricoides, Bacteroides uniformis, Bacteroides vulgatus, Bacteroides-Prevotella group, Barnesiella spp., Beta-glucuronidase, Bifidobacterium longum, Bifidobacterium longum subsp. longum, Bifidobacterium spp., Blastocystis spp., Butyrivibrio crossotus, Calprotectin, Candida albicans/dubliniensis, Capillaria philippinensis, Cholesterol, Citrobacter species, Clostridium spp., Collinsella aerofaciens, Coprococcus eutactus, Cryptosporidium parvum/hominis, Cyclospora cayetanensis, Desulfovibrio piger, Dientamoeba fragilis, Entamoeba histolytica, Enterobacter cloacae, Enterobius vermicularis, Enterococcus faecalis, Eosinophil Protein X, Escherichia coli, Faecalibacterium prausnitzii, Fecal Color, Fecal Consistency, Fecal Fat, Total, Fecal Occult Blood, Fecal secretory IgA, Firmicutes/Bacteroidetes (F/B Ratio), Fusobacterium spp., Giardia, Klebsiella oxytoca, Klebsiella species, Lactobacillus spp., Long-Chain Fatty Acids, Methanobrevibacter smithii, n-Butyrate %, n-Butyrate Concentration, Odoribacter spp., Oxalobacter formigenes, Pancreatic Elastase 1, Phocaeicola vulgatus, Phospholipids, Prevotella spp., Products of Protein Breakdown (Total), Propionate, Proteus mirabilis, Pseudoflavonifractor spp., Roseburia spp., Ruminococcus bromii, Ruminococcus spp., Short-Chain Fatty Acids (SCFA), Total, Triglycerides, Veillonella spp., Zonulin Family Peptide
