Beta-glucuronidase is an enzyme produced by certain unfriendly gut bacteria. A proper balance of beta-glucuronidase is essential for good health and disease prevention.
What is Glucuronidation?
Glucuronidation is an essential detoxification proocess that inactivates and detoxifies hormones, neurotransmitters, drugs, mold toxins, and cancer-causing toxins.
References:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982897/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2813552/
https://www.ncbi.nlm.nih.gov/pubmed/12197785
https://europepmc.org/abstract/med/18772850
https://www.hindawi.com/journals/jnme/2015/760689/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858007/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858007/
https://www.ncbi.nlm.nih.gov/pubmed/25799848
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858007/
https://www.ncbi.nlm.nih.gov/pubmed/9148858
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858007/
https://www.ncbi.nlm.nih.gov/pubmed/8019514
https://europepmc.org/abstract/med/18772850
https://www.sciencedirect.com/science/article/pii/030438359090083A
https://www.ncbi.nlm.nih.gov/pubmed/14595593
Beta-glucuronidase is an enzyme that is used to digest carbohydrates and is a product of E. coli and anaerobic bacteria (bacteroides and clostridia). It is a key component of phase II detoxification (glucuronidation pathway) that helps clear pharmaceuticals, carcinogens, bile acids, and estrogen. Low levels would suggest a lack of E. coli and anaerobes or an overutilization of the glucuronidation pathway due to high toxic load. This can be difficult to interpret. But we generally want more beta-glucuronidase.
If low levels, replenish healthy bacteria and reduce toxic load.
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High levels of beta glucuronidase inhibits this glucuronidation process to detoxify the body from both natural hormones (ex: estrogens) and various environmental toxins.
High levels of beta-glucuronidase in the stool can be caused by a number of factors which are primarily due to the following diet and lifestyle habits:
– High fat diet
– Processed food consumption
– Sugar consumption
– Alcohol consumption
– Smoking
Taking antibiotics can also increase beta-glucuronidase as antibiotics destroy gut bacteria.
The following cancers have been identified with high beta-glucuronidase levels:
– Colon cancer
– Prostate cancer
– Breast cancer
How to lower Beta-glucuronidase levels?
In order to maintain good health and to lower the risk of the above referenced cancers, it is important to keep beta-glucuronidase activity low but sufficient enough to assist in the nutrient absorption process. Adhering to a low fat, whole food plant-based diet could be an important step to decrease Beta-glucuronidase
There are also some specific natural substances that may lower Beta-glucuronidase:
– Apple Pectin
– Calcium, iron, magnesium
– Calcium-D-Glucarate
– Milk thistle (Silymarin)
– Cumin / black pepper
– Fenugreek Seeds
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Acetate, Akkermansia muciniphila, alpha haemolytic Streptococcus, Anaerotruncus colihominis, Anaerotruncus colihominis/massiliensis, Ancylostoma/Necator (Hookworm), Ascaris lumbricoides, Bacteroides uniformis, Bacteroides vulgatus, Bacteroides-Prevotella group, Barnesiella spp., Beta-glucuronidase, Bifidobacterium longum, Bifidobacterium longum subsp. longum, Bifidobacterium spp., Blastocystis spp., Butyrivibrio crossotus, Calprotectin, Candida albicans/dubliniensis, Capillaria philippinensis, Cholesterol, Citrobacter species, Clostridium spp., Collinsella aerofaciens, Coprococcus eutactus, Cryptosporidium parvum/hominis, Cyclospora cayetanensis, Desulfovibrio piger, Dientamoeba fragilis, Entamoeba histolytica, Enterobacter cloacae, Enterobius vermicularis, Enterococcus faecalis, Eosinophil Protein X, Escherichia coli, Faecalibacterium prausnitzii, Fecal Color, Fecal Consistency, Fecal Fat, Total, Fecal Occult Blood, Fecal secretory IgA, Firmicutes/Bacteroidetes (F/B Ratio), Fusobacterium spp., Giardia, Klebsiella oxytoca, Klebsiella species, Lactobacillus spp., Long-Chain Fatty Acids, Methanobrevibacter smithii, n-Butyrate %, n-Butyrate Concentration, Odoribacter spp., Oxalobacter formigenes, Pancreatic Elastase 1, Phocaeicola vulgatus, Phospholipids, Prevotella spp., Products of Protein Breakdown (Total), Propionate, Proteus mirabilis, Pseudoflavonifractor spp., Roseburia spp., Ruminococcus bromii, Ruminococcus spp., Short-Chain Fatty Acids (SCFA), Total, Triglycerides, Veillonella spp., Zonulin Family Peptide