Pentatrichomonas hominis, belonging to the Trichomonadidae, inhabits the digestive tract of several vertebrates such as humans, monkeys, pigs, dogs, cats and rats. This species was originally considered a commensal protozoan of the digestive tract but has subsequently been identified as a potential zoonotic parasite and a causative agent of diarrhea.
Fecal contamination of food or water
- Considered harmless, a non-pathogen
- Infected individuals are usually asymptomatic
- May contribute to dysbiosis
- Also colonizes dogs, cats, and other animals
Pentatrichomonas hominis has been associated with irritable bowel syndrome, systemic lupus erythematosus and rheumatoid arthritis in humans.
One specific study showed that a significantly higher prevalence of P. hominis was found in cancer patients than that in the control population. Pentatrichomonas hominis infection can cause a 6.75-fold risk of gastrointestinal cancers.
The high prevalence of P. hominis was not only observed in colorectal cancer, but also in other gastrointestinal cancers, including stomach cancer, liver cancer, esophageal cancer and small intestine cancer [L].
Therapeutic Options and Considerations:
- May be asymptomatic
- In women with vaginosis, consider treatment to reduce chances of vaginal contamination or reinfection (find treatments for Trichomonas vaginalis elsewhere)
- If treatment is needed, consider a broad-spectrum antiparasitic herbal formula
- Consider probiotics and the 5R Protocol (see this blog post)
- Look for and address sources of fecal contamination
- Address other imbalances on the GI-MAP
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