Faecalibacterium prausnitzii is one of the most important bacteria in the human gut flora and makes up to 5-10% of the total number of bacteria detected in stool samples from healthy humans. Faecalibacterium prausnitzii has a crucial role in maintaining gut physiology and host wellbeing.
Faecalibacterium prausnitzii monitoring may serve as a biomarker to assist in gut diseases diagnostics.
Faecalibacterium prausnitzii has been consistently reported as one of the main butyrate producers found in the intestine. Butyrate has a crucial role in gut physiology and host wellbeing. It is the main energy source for the colonocytes and it has protective properties against colorectal cancer (CRC) and inflammatory bowel diseases.
Faecalibacterium prausnitzii is a major butyrate-producing species, that is particularly abundant in the colon.
Reduced levels of F. prausnitzii have been found in several intestinal diseases, such as Crohn’s disease, ulcerative colitis, and colorectal cancer, as well as in a number of other chronic diseases.
Various studies have shown that Faecalibacterium prausnitzii abundance is reduced in different intestinal disorders.
In healthy adults, Faecalibacterium prausnitzii represent more than 5% of the bacteria in the intestine, making it one of the most common gut bacteria. It boosts the immune system, among other things. Higher than usual levels have been associated with psoriasis.
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