Prevotella spp. are obligate anaerobic, Gram-negative rod-shaped bacteria belonging to the Prevotellaceae family. The genus comprises approximately 30 species.
Prevotella are bacteria that inhabit many parts of the body. Although common in the gut microbiome, if found elsewhere, they may be a sign of trouble or infection.
Prevotella spp. is known for its ability to degrade complex plant polysaccharides (carbohydrates) and fiber.
Prevotella spp. is known for its ability to degrade complex plant polysaccharides (carbohydrates) and fiber.
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- Higher levels of Prevotella spp. are found in populations who eat high fiber diets. Higher levels have also been associated with smokers.
- In a recent study the number of Prevotella in IBS-D patients was over 100-fold higher when compared with healthy subjects [L]
- Prevotella may interact with other microbiota to induce visceral hypersensitivity and exacerbate symptom of IBS by promoting carbohydrate fermentation. [L]
- Prevotella contains enzymes that are important in mucin degradation, which may lead to increased intestinal permeability. [L]
- The conclusion of another recent study was that Prevotella spp in the gut microbiota are associated with the rheumatoid arthritis genotype in the absence of rheumatoid arthritis, including in individuals at high risk of developing rheumatoid arthritis. [L]
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