Calprotectin is a calcium-binding protein with antimicrobial properties. It accounts for 60% of neutrophil cytosolic content and is also found in monocytes and macrophages. Calprotectin is released from the intestinal mucosa into the stool in intestinal inflammation.
According to the literature, calprotectin levels can vary with age. It is higher in children younger than 5 years old due to increased intestinal mucosal permeability and differences in intestinal flora.
Fecal calprotectin for children between 2 to 9 years is considered normal if <166 mcg/g,
in individuals between 10 and 59 years if <51 mcg/g,
and after 60 years if <112 mcg/g.69
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