Gluten Peptide
Fecal Gluten Peptide quantitatively evaluates the gluten immunogenic peptide in stool after recent ingestion (within 2 to 4 days). Results can guide practitioners to the source of "hidden" gluten exposures – allowing for increased adherence to a proper therapeutic diet.
Gluten Peptide is commonly present in stool. Gluten-containing grains (such as wheat, rye, barley, and oat*) are digested into their gliadin and glutenin subunits. A specific section of the gliadin protein, referred to as the 33-mer peptide, is resistant to digestion in the human gastrointestinal (GI) tract and functions as a significant immune trigger in certain individuals, including those with celiac disease (CD). Even in non-celiac gluten-sensitive (NCGS) individuals, the 33-mer protein can be antigenic, inducing food sensitivities and intestinal permeability (leaky gut). When intestinal permeability is present, this antigenic peptide can drive extra-intestinal symptoms – those presenting outside the GI tract – such as skin manifestations, headaches, behavioral symptoms, and more.
What does it mean if your Gluten Peptide result is too high?
The Fecal Gluten Peptide Add-On (Stool Gluten) is an accurate and noninvasive method that enables a direct, quantitative assessment of gluten consumption. The amount of gluten peptide detected in stool rises in proportion to the amount of gluten consumed. Thus, the test can be useful for monitoring occasional exposures or exposures that may be routine in a persons' lifestyle (even if they are unknown).
This test is a direct quantification of the 33-mer gliadin peptide present in stool samples. Because this peptide is highly resistant to human digestion, it can be accurately detected in a person's stool several days after consumption of gluten.
Currently, the only approach to managing celiac disease is to maintain a strict gluten-free (GF) diet for life. Additionally, as non-celiac gluten-related disorders are emerging more and more in literature and clinical practice, many people choose to be gluten-free to reduce GI inflammation and associated symptoms, and to prevent or heal intestinal permeability.
Although conceptually straight forward, there are inherent challenges to following a GF diet as recommended. Estimated compliance rates vary considerably (anywhere from 17–80%) depending on factors such as patient age, age of diagnosis, income, gender, and others. Celiac.org cites that up to 50% of celiac patients still report symptoms while following a GF diet. There are abundant opportunities for accidental exposure to gluten from hidden food sources and even medications. Food labeling and label reading is an added complication and a 2019 study found that up to 32% of restaurant-labeled GF foods can be cross contaminated.
The importance of monitoring a GF diet is obvious, however there are currently no clear guidelines for exploring adherence or assessing the outcome. Recent studies suggest that patients cannot rely on dietary best practices or even symptoms to understand if they have been exposed to gluten.
All Your Lab Results.
One Simple Dashboard.
Import, Track, and Share Your Lab Results Easily
Import, Track, and Share Your Lab Results
Import lab results from multiple providers, track changes over time, customize your reference ranges, and get clear explanations for each result. Everything is stored securely, exportable in one organized file, and shareable with your doctor—or anyone you choose.
Cancel or upgrade anytime
Laboratories
Bring All Your Lab Results Together — In One Place
We accept reports from any lab, so you can easily collect and organize all your health information in one secure spot.
Pricing Table
Gather Your Lab History — and Finally Make Sense of It
Finally, Your Lab Results Organized and Clear
Personal plans
$79/ year
Advanced Plan
Access your lab reports, explanations, and tracking tools.
- Import lab results from any provider
- Track all results with visual tools
- Customize your reference ranges
- Export your full lab history anytime
- Share results securely with anyone
- Receive 5 reports entered for you
- Cancel or upgrade anytime
$250/ once
Unlimited Account
Pay once, access everything—no monthly fees, no limits.
- Import lab results from any provider
- Track all results with visual tools
- Customize your reference ranges
- Export your full lab history anytime
- Share results securely with anyone
- Receive 10 reports entered for you
- No subscriptions. No extra fees.
$45/ month
Pro Monthly
Designed for professionals managing their clients' lab reports
- Import lab results from any provider
- Track lab results for multiple clients
- Customize reference ranges per client
- Export lab histories and reports
- Begin with first report entered by us
- Cancel or upgrade anytime
About membership
What's included in a Healthmatters membership
Import Lab Results from Any Source
See Your Health Timeline
Understand What Your Results Mean
Visualize Your Results
Data Entry Service for Your Reports
Securely Share With Anyone You Trust
Let Your Lab Results Tell the Full Story
Once your results are in one place, see the bigger picture — track trends over time, compare data side by side, export your full history, and share securely with anyone you trust.
Bring all your results together to compare, track progress, export your history, and share securely.
What Healthmatters Members Are Saying
Frequently asked questions
Healthmatters is a personal health dashboard that helps you organize and understand your lab results. It collects and displays your medical test data from any lab in one secure, easy-to-use platform.
- Individuals who want to track and understand their health over time.
- Health professionals, such as doctors, nutritionists, and wellness coaches, need to manage and interpret lab data for their clients.
With a Healthmatters account, you can:
- Upload lab reports from any lab
- View your data in interactive graphs, tables, and timelines
- Track trends and monitor changes over time
- Customize your reference ranges
- Export and share your full lab history
- Access your results anytime, from any device
Professionals can also analyze client data more efficiently and save time managing lab reports.
Healthmatters.io personal account provides in-depth research on 10000+ biomarkers, including information and suggestions for test panels such as, but not limited to:
- The GI Effects® Comprehensive Stool Profile,
- GI-MAP,
- The NutrEval FMV®,
- The ION Profile,
- Amino Acids Profile,
- Dried Urine Test for Comprehensive Hormones (DUTCH),
- Organic Acids Test,
- Organix Comprehensive Profile,
- Toxic Metals,
- Complete Blood Count (CBC),
- Metabolic panel,
- Thyroid panel,
- Lipid Panel,
- Urinalysis,
- And many, many more.
You can combine all test reports inside your Healthmatters account and keep them in one place. It gives you an excellent overview of all your health data. Once you retest, you can add new results and compare them.
If you are still determining whether Healthmatters support your lab results, the rule is that if you can test it, you can upload it to Healthmatters.
We implement proven measures to keep your data safe.
At HealthMatters, we're committed to maintaining the security and confidentiality of your personal information. We've put industry-leading security standards in place to help protect against the loss, misuse, or alteration of the information under our control. We use procedural, physical, and electronic security methods designed to prevent unauthorized people from getting access to this information. Our internal code of conduct adds additional privacy protection. All data is backed up multiple times a day and encrypted using SSL certificates. See our Privacy Policy for more details.