Zonulin is a protein that opens intercellular tight junctions in the gut lining (the connections between epithelial cells that make up the gastrointestinal lining). Zonulin increases intestinal permeability in the jejunum and ileum and is considered a biomarker for barrier permeability.
Therapeutic Approach for Elevated Intestinal Permeability:
- Address dysbiosis (pathogens and opportunistic microbe overgrowth, lack of beneficial microbes)
- Eliminate gluten, address potential food sensitivities
- Promote a healthy intestinal barrier with L-glutamine, butyrate, essential fatty acids, aloe vera, probiotics, zinc carnosine, slippery elm, marshmallow, deglycyrrhizinated licorice.
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