- Morganella spp. is a gram-negative group in the Proteobacteria phylum. The Proteobacteria are a major group (phylum) of bacteria. They include a wide variety of pathogens, such as Escherichia, Salmonella, Vibrio, Helicobacter, and many other notable genera. Others are free-living, and include many of the bacteria responsible for nitrogen fixation.
- Morganella spp. may produce histamine. Histamine is an organic nitrogenous compound involved in local immune responses, as well as regulating physiological function in the gut and acting as a neurotransmitter for the brain, spinal cord, and uterus. Histamine is involved in the inflammatory response and has a central role as a mediator of itching.
- High levels may indicate increased intestinal inflammatory activity.
- High levels may cause diarrhea, and may also be associated with SIBO.
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