A healthy result should fall into the range 0 - 9.3 mcg/mg creatinine.

Benzoate, was one of the compounds first found to be elevated in urine from patients with intestinal bacterial overgrowth of various origins. Many people with intestinal bacterial overgrowth resulting from cystic fibrosis, unclassified enteritis, celiac disease, or short bowel syndrome have elevated benzoate along with varying degrees of elevated phenylacetate, p-hydroxybenzoate, and p-hydroxyphenylacetate.

Benzoic acid, a common food component used as a preservative in packaged foods such as pickles and lunch meats, also occurs naturally in cranberries and other fruits, a factor to take into account when interpreting elevated hippurate levels in urine. Whether the source is dietary intake or jejunal bacterial metabolism, benzoate should be rapidly converted to hippurate by conjugation with glycine.

What is Hippurate?

Hippurate is produced by the conjugation of Benzoate and glycine, found as a normal component in urine as a metabolite of aromatic compounds from food. Increased urine hippuric acid content may have antibacterial effects.

What is Glycine?

Glycine is an amino acid serving several important purposes within the body, including:

- Detoxification,

- DNA formation,

- The synthesis of hemoglobin,

- and as a part of brain neurotransmission pathways.

- In the liver, glycine helps to convert many potentially harmful substances, including toxic materials such as benzoic acid (benzoate) into harmless forms.

References:
– van der Heiden C, Wauters EA, Duran M, et al. Gas chromatographic analysis of urinary
tyrosine and phenylalanine metabolites in patients with gastrointestinal disorders. Clin Chim Acta, 1971;34:289-296.
– Temellini A, Mogavero S, Giulianotti PC, et al. Conjugation of benzoic acid with glycine in human liver and kidney: a study on the interindividual variability. Xenobiotica 1993;23:1427-1433.
 

Benzoate result calculator

insert the value from you Benzoate test result.

What does it mean if your Benzoate result is too high?

- Elevated benzoate is a confirmatory marker for inadequacy of glycine or pantothenic acid for conjugation reactions.

- Abnormalities of urinary benzoate and hippurate may reveal clinically significant detoxification or dysbiosis (=microbial imbalance ).

- High benzoate indicates poor detoxification via phase II glycine conjugation.

Are you concerned about your lab report?
Select your plan, upload your lab reports and we’ll provide you with a meaningful interpretation.

Basic Interpretation
  • Instant interpretation
  • Use self upload form
  • 800+ biomarkers explained
  • Nutrition Recommendations
  • Cancel anytime
Full Interpretation
  • Instant interpretation
  • We upload 4 reports for you
  • 800+ biomarkers explained
  • Nutrition Recommendations
  • Cancel anytime
  • Online support
Own It For Life
  • Unlimited access
  • No subscription
  • Instant interpretations
  • We upload 10 reports for you
  • 800+ biomarkers explained
  • Nutrition Recommendations
  • Dedicated support

Test results don't lie. Learn what is happening inside your body.

Health is not exactly rocket science. You just have to know what your body needs and doesn't need. Your medical tests contain that information. Upload them to our service and we’ll help you understand, organize, and act on them.

Get Started

Medical results explained and interpreted.

WE SUPPORT 1000+ BIOMARKERS INCLUDING BIOMARKERS FROM YOUR FAVOURITE LABS

Healthmatters.io customer review

"I was really concerned about my lab results and my GP was not able to see me for another week. Through HealthMatters I was able to interpret my results instantly."

Healthmatters.io thankfull female customer

"I've been keeping all my lab results in a spreadsheet, covering approximately 20 years. The HealthMatters team helped me upload that info into the cloud. I can show this data to my family and doctors now easily."

Healthmatters.io thankful young female customer

"I had no idea what my lab results meant. Here I found all the biomarkers that I was looking for online. Finally, I have not only organized them all neatly in one place, but I am also grateful to be able to understand what they mean."



Pricing
Privacy and security of personal data. HIPAA and GDPR compliant badges.

Your Privacy And Security

At HealthMatters, we're committed to maintaining the security and confidentiality of your personal information. We've put security measures in place to help protect against the loss, misuse or alteration of information under our control. We use procedural, physical and electronic security methods designed to prevent people who aren't authorized from getting access to this information. Our internal code of conduct adds additional privacy protection. See our Privacy Policy for more information.