8-hydroxy-2-deoxyguanosine measures the oxidative impact to DNA. 8-hydroxy-2-deoxyguanosine levels will be high if your total antioxidant protection is inadequate.
8-hydroxy-2-deoxyguanosine is a non-invasive marker of cell damage. Some cell damage is a normal part of metabolism, but it is kept to a minimum by the cell’s protective mechanisms. Under certain circumstances, the balance between the damaging chemicals and protective mechanisms can be upset, resulting in a condition termed “oxidative stress.” Although numerous cell damage products can be formed, the one most often studied is 8-OHdG. When oxidative damage occurs to the cells, repair mechanisms produce 8-OHdG, which is excreted unchanged in the urine. High levels reflect high oxidative stress to the cells.a
8-Hydroxy-2-deoxyguanosine
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