A healthy result should fall into the range 0 - 6.3 mcg/mg creatinine.

Ethylmalonate, together with Adipate and Suberate, gives information about your ability to process fatty acids.

Ethylmalonate, which comes from the breakdown of butyrate, has a carnitine-dependent pathway and can accumulate with an insufficient amount of carnitine. Dietary fat, carbohydrate, and protein are all broken down to produce energy using pathways that require vitamin B2 (riboflavin).

If you do not have sufficient riboflavin, compounds such as adipate, suberate, and ethylmalonate may increase in urine.

What is Carnitine?

Carnitine helps your body use fatty acids. The body makes small amounts of carnitine.

However, if minimum requirements are not met, carnitine dependent functions fail to proceed normally. Long-chain fatty acids go through beta-oxidation in the mitochondria, which is a carnitine dependent step.

If there are inadequate amounts of carnitine, the long-chain fatty acids will get processed outside of the mitochondria; Adipate and suberate are by-products of long-chain fatty acid breakdown outside of the mitochondria.

References:

Ethylmalonate result calculator

insert the value from you Ethylmalonate test result.

What does it mean if your Ethylmalonate result is too high?

Adipate, Suberate, and Ethylmalonate elevations indicate metabolic blocks. Carnitine is needed to move fatty acids into the mitochondria where they are converted to energy using vitamin B2. When insufficient levels of carnitine or vitamin B2 slow down this process, other parts of the cellular machinery take over and make adipate and suberate. A similar block in another pathway causes high ethylmalonate. Since most of your body’s energy is produced from the burning of fatty acids, your muscles and brain suffer when this cellular energy pathway is blocked.

Treatment:

Supplementation of carnitine and vitamin B2 may be needed when these compounds are too high. Insufficiency of vitamin B2 is implicated in impaired carbohydrate metabolism, migraines, and dementia. Carnitine supplementation has been documented to improve Alzheimer’s, age-related cognitive decline, and cardiac function.



Upload Full Test and Learn More

To learn more, visualize and track your test results, create a personal account.

Sign Up, Upload Tests, Get Insights and Improve with HealthMatters.io.

Sign up now.

Are you concerned about your blood test results?
Then get your personal health dashboard.

$5,99/month

Personal Plan +

Unlimited Tests Upload Subscription
Cancel anytime

Sign Up

$10/test

Personal Plan Basic

Single test upload.
Pay for each test result upload.

Upload Now

Your Privacy And Security

At HealthMatters, we're committed to maintaining the security and confidentiality of your personal information. We've put security measures in place to help protect against the loss, misuse or alteration of information under our control. We use procedural, physical and electronic security methods designed to prevent people who aren't authorized from getting access to this information. Our internal code of conduct adds additional privacy protection. See our Privacy Policy for more information.