Endocrinology

ACTH, Plasma

A healthy result should fall into the range 7.2 - 63.3 pg/mL.

ACTH is a pituitary hormone that stimulates the production of cortisol from the adrenal glands. Cortisol levels are usually highest between 6 and 8 a.m. and at the lowest around 11 p.m. 

Cortisol is the hormone that is released during stress. It essentially revs up your body so you can handle the stress you are encountering. One of the types of stress you can experience is physiological stress, or negative things that are happening within your metabolism such as low blood sugar or high blood sugar.  

ACTH levels vary during the day. If it’s too high or too low, you may be diagnosed with Cushing’s syndrome. If it’s too high, you may have Addison disease, or if too low, you may have a low functioning pituitary.

Normal Ranges for ACTH in pg/mL:

Adults/children: 7.2-63 pg/mL

Females 5-27 pg/mL   Males 7-50 pg/mL

Prepuberty: 7-28 pg/mL

Postpuberty: 2-49 pg/mL

These values are for morning draws, not evening draws.

 

Sources:

  1. https://www.mayomedicallaboratories.com/test-catalog/Overview/8411
  2. https://emedicine.medscape.com/article/2088760-overview
  3. https://www.urmc.rochester.edu/encyclopedia/content.aspx?ContentTypeID=167&ContentID=acth_blood 

ACTH, Plasma result calculator

insert the value from you ACTH, Plasma test result.

What does it mean if your ACTH, Plasma result is too low?

Decreased levels of ACTH are seen in the following conditions:

- Congenital ACTH deficiency

- Skull fracture that causes a traumatic brain injury

- Hypophysitis, either autoimmune or drug-induced

- Hypothalamus diseases from infections

- Pituitary adenoma

- Infection of the pituitary

- Radiotherapy of the pituitary

- Hemorrhage of the pituitary

- Sella turcica lesions

- Pituitary corticotroph disease

- Glucocorticoid medication

What does it mean if your ACTH, Plasma result is too high?

High levels of ACTH may result from any of the following conditions: 

- Cushing’s disease (pituitary adenoma)

- Non-pituitary tumor 

- Depression

- Alcoholism

- Anorexia nervosa

- Primary adrenal insufficiency (called Addison disease)

- Congenital adrenal hyperplasia

- 21-hydroxylase or 17-alpha-hydroxylase deficiency

- 3-beta-hydroxysteroid dehydrogenase deficiency

- Cholesterol side-chain cleavage enzyme deficiency

- Nelson syndrome (patients with Cushing’s disease that have had adrenal glands removed) 

- Those who have developed human antimouse antibodies or heterophilic antibodies

Are you concerned about your lab report?
Select your plan, upload your lab reports and we’ll provide you with a meaningful interpretation.

Basic Interpretation
  • Instant interpretation
  • Use self upload form
  • 800+ biomarkers explained
  • Nutrition Recommendations
  • Cancel anytime
Full Interpretation
  • Instant interpretation
  • We upload 4 reports for you
  • 800+ biomarkers explained
  • Nutrition Recommendations
  • Cancel anytime
  • Online support
Own It For Life
  • Unlimited access
  • No subscription
  • Instant interpretations
  • We upload 10 reports for you
  • 800+ biomarkers explained
  • Nutrition Recommendations
  • Dedicated support

Test results don't lie. Learn what is happening inside your body.

Health is not exactly rocket science. You just have to know what your body needs and doesn't need. Your medical tests contain that information. Upload them to our service and we’ll help you understand, organize, and act on them.

Get Started

Medical results explained and interpreted.

WE SUPPORT 1000+ BIOMARKERS INCLUDING BIOMARKERS FROM YOUR FAVOURITE LABS

Healthmatters.io customer review

"I was really concerned about my lab results and my GP was not able to see me for another week. Through HealthMatters I was able to interpret my results instantly."

Healthmatters.io thankfull female customer

"I've been keeping all my lab results in a spreadsheet, covering approximately 20 years. The HealthMatters team helped me upload that info into the cloud. I can show this data to my family and doctors now easily."

Healthmatters.io thankful young female customer

"I had no idea what my lab results meant. Here I found all the biomarkers that I was looking for online. Finally, I have not only organized them all neatly in one place, but I am also grateful to be able to understand what they mean."



Pricing
Privacy and security of personal data. HIPAA and GDPR compliant badges.

Your Privacy And Security

At HealthMatters, we're committed to maintaining the security and confidentiality of your personal information. We've put security measures in place to help protect against the loss, misuse or alteration of information under our control. We use procedural, physical and electronic security methods designed to prevent people who aren't authorized from getting access to this information. Our internal code of conduct adds additional privacy protection. See our Privacy Policy for more information.