Endocrinology

DHEAS (Serum)

A healthy result should fall into the range 9.58 - 405.306 mcg/dL, or 0.26 - 10.98 umol/L.

It stands for Dehydroepiandrosterone and is a building block of steroid hormones that is produced predominantly in the adrenal glands. It serves as a precursor to the sex hormone testosterone and estrogen in both men and women. DHEA is also a building block of the stress hormone cortisol and supports immune system function. DHEA may also increase insulin sensitivity, enhance fat metabolism, and act as an antioxidant. There are two type of dehydroepiandrosterone: DHEA and its sulfate form, dehydroepiandrosterone sulfate (DHEAS). Because DHEAS remains in the bloodstream longer than DHEA, doctors generally test DHEAS numbers when they suspect a problem with this hormone. Typically, DHEAS levels are high in newborns and drop significantly after birth. They increase during puberty, peak soon after, and decline with age. Normal ranges are as follows: 

Men:

18 to 19 -- 108 to 441 mcg/dL

20 to 29 -- 280 to 640 mcg/dL

30 to 39 -- 120 to 520 mcg/dL

40 to 49 -- 95 to 530 mcg/dL

50 to 59 -- 70 to 310 mcg/dL

60 to 69 -- 42 to 290 mcg/dL

69 and older -- 28 to 175 mcg/dL

Women:

18 to 19 -- 145 to 395 mcg/dL

20 to 29 -- 65 to 380 mcg/dL

30 to 39 -- 45 to 270 mcg/dL

40 to 49 -- 32 to 240 mcg/dL

50 to 59 -- 26 to 200 mcg/dL

60 to 69 -- 13 to 130 mcg/dL

69 and older -- 17 to 90 mcg/dL

Keep in mind that reference ranges can differ from lab to lab, so check the listing on your blood test for the range that applies to you.

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