Kynurenic Acid

Optimal Result: 0 - 7.1 mmol/mol creatinine.

Kynurenic Acid is product of the metabolism of L-Tryptophan and appears in urine in Vitamin B6 deficiencies. Your body needs vitamin B6 (pyridoxine) to utilize amino acids derived from dietary protein. Inadequate vitamin B6 is one factor that leads to increased concentrations of kynurenate and xanthurenate in urine. These products of amino acid breakdown cannot be further metabolized in the absence of vitamin B6.



What does it mean if your Kynurenic Acid result is too low?

Research shows that kynurenic acid is low with a low protein diet and in autism spectrum disorder. Low kynurenic acid is implicated in depression, headaches, bipolar disorder, and Alzheimer’s disease.

What does it mean if your Kynurenic Acid result is too high?

- A high reading of this by-product of the breakdown of the amino acid tryptophan is consistent with a vitamin B6 deficiency, possible inflammatory processes, interferon-gamma stimulated macrophages or excessive tryptophan supplementation (not 5-HTP).

- Abnormally high levels can cause and increase in pain sensations and may, in multiple sclerosis patients, be a marker for an exacerbation period.

- Vitamin B6 deficiency may also result in elevated concentrations of homocysteine in blood, which leads to increased risk of heart disease.

- High levels of Kynurenic Acid can have direct effects on brain function in addition to showing a need for vitamin B6.

- High values in individuals with the yeast overgrowth syndrome may be due to yeast interference.

10 000+ happy customers
100% satisfaction
★ ★ ★ ★ ★ customer support

Trust us to examine your lab results, guiding you towards improved health.

Use promo code to save 10% off any plan.

We implement proven measures to keep your data safe.

At HealthMatters, we're committed to maintaining the security and confidentiality of your personal information. We've put industry-leading security standards in place to help protect against the loss, misuse, or alteration of the information under our control. We use procedural, physical, and electronic security methods designed to prevent unauthorized people from getting access to this information. Our internal code of conduct adds additional privacy protection. All data is backed up multiple times a day and encrypted using SSL certificates. See our Privacy Policy for more details.