Optimal Result: 0 - 0.97 mmol/mol creatinine.

Alpha-Ketoisovalerate (together with Alpha-Ketoisocaproate and Alpha-Keto-Beta-methylvalerate) requires Vitamins B1, B2, B3, B5 and lipoic acid to be metabolized.

Nutrient associations: Vitamins B1, B2, B3, B5

What do elevations mean?

Elevations of these organic acids can indicate insufficiency of these B vitamins, especially B1 and B5.

Why are these B vitamins so critical?

These B vitamins are involved in neurological function and are critical for childhood development and learning. A variety of disorders have been associated with lack of these vitamins, including memory loss, anemia, and dermatitis.

Vitamins B1 (thiamin), B3 (niacin), and B5 (pantothenic acid) are necessary for energy pathways of all of the cells in your body. As food is broken down in your body, specific compounds are formed (such as Alpha-Ketoisovalerate) at steps that require B vitamin assistance.

If very low normal result:

- Low B6

- Low branched chain amino acids

What does it mean if your a-Ketoisovaleric Acid result is too high?

Possible causes:

- Impaired metabolism due to cofactor insufficiencies or toxic metals

- “Maple syrup urine disease” if markedly elevated.

Additional investigations:

- Vitamins & Minerals Analysis

- Comprehensive Urine Elements Profile

Treatment considerations:

- Supplement cofactors: B1, B2, B3, B5, Mg, cysteine or lipoic acid

- Remove toxic metals: As, Hg, Pb, Cd

 

Understand blood, stool, and urine medical results from your labs.

10 000+ happy clients
100% satisfaction
★★★★★ customer support

Get 10% off of your first yearly or monthly plan.

Use promocode

Essential Plan


  • Monthly subscription
  • Instant interpretation
  • Use the free self-upload form
  • Additional charge for upload service
  • 2000+ biomarkers explained
  • Recommendations
  • Cancel anytime

Advanced Plan


  • Yearly subscription
  • Instant interpretation
  • We upload five reports for you
  • Use the free self-upload form
  • 2000+ biomarkers explained
  • Nutrition Recommendations
  • Online support
  • Cancel anytime

Own It For Life premium plan


  • No subscription
  • Unlimited access
  • Unlimited storage
  • Instant interpretations
  • We upload ten reports for you
  • Use the free self-upload form
  • 2000+ biomarkers explained
  • Nutrition Recommendations
  • Dedicated support

Healthmatters.io software for professional use.

Welcome to Healthmatters Pro.

Save time on interpreting lab results with the largest database of biomarkers online. In-depth research on any test at your fingertips, all stored and tracked in one place.

Learn More


We implement proven measures to keep your data safe.

At HealthMatters, we're committed to maintaining the security and confidentiality of your personal information. We've put industry-leading security standards in place to help protect against the loss, misuse, or alteration of the information under our control. We use procedural, physical, and electronic security methods designed to prevent unauthorized people from getting access to this information. Our internal code of conduct adds additional privacy protection. All data is backed up multiple times a day and encrypted using SSL certificates. See our Privacy Policy for more details.

General Data Protection Regulation (GDPR). HIPAA compliance for healthcare professionals
×

Understand Your Lab Result Now

  • Instant interpretation
  • 2000+ biomarkers explained
  • Science-based recommendations
  • Online support
  • Secure and private portal

Get 10% off with promocode:

;