If you can test it, we can track it — all test results, including the ones from your favorite labs.

Optimal Result: 0 - 19 mmol/mol creatinine.

Homogentisic acid, also known as melanic acid, is an intermediate in the breakdown or catabolism of tyrosine and phenylalanine.

References:

http://www.hmdb.ca/metabolites/HMDB0000130

What does it mean if your Homogentisic Acid result is too high?

Possible causes:

- Impaired metabolism due to cofactor insufficiency (iron, vitamin C, 02)

- Chronically high levels of homogentisic acid are associated with alkaptonuria, an inborn error of metabolism. Alkaptonuria is a rare inherited genetic disorder in which the body cannot process the amino acids phenylalanine and tyrosine.

Additional investigations:

- Iron studies

Treatment considerations:

- Supplement iron if low

- Vitamin C

- Improve oxygenation

If you can test it, we can track it — all test results, including the ones from your favorite labs.

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