Optimal Result: 0 - 0.51 mmol/mol creatinine.

Glutaric acid is made from lysine & tryptophan via alphaketo-adipic acid.

What does it mean if your Glutaric Acid result is too high?

Elevation indicates riboflavin (vitamin B2) deficiency. Other possible factors include fatty acid oxidation defects, and metabolic effects of valproic acid (Depakene), or celiac disease. The probability of a genetic disease is higher with very high values. The use of dietary supplements containing riboflavin and coenzyme Q10 may improve clinical symptoms. This compound may be elevated in about 10% of children with autism.

Possible causes:

- Low B2

- Inborn error of metabolism

- Associated with CETP genetic polymorphism

Additional investigations:

- Red blood cell B2

- Genetic Diagnostic Testing

Treatment considerations:

- Supplement B2

- Consider mitochondrial support nutrients (e.g. CoQ10)


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