Optimal Result: 0 - 1.7 mmol/mol creatinine.

Alpha-Ketoadipic acid (or 2-oxoadipate) is an intermediate in the metabolism of lysine. It is made from tryptophan & lysine via alpha-aminoadipic acid. It is also a byproduct of yeast.

What does it mean if your a-Ketoadipic Acid result is too high?

Possible causes:

- May be secondary to high glutaric acid (check glutaric acid level)
- Impaired metabolism due to cofactor insufficiencies
- Toxic metals (As, Hg, Sb, Cd)
- Secondary to yeast or fungal infection

Additional investigations:

- Vitamins & Minerals Analysis
- Comprehensive Urine Elements Profile
- Complete Digestive Stool Analysis

Treatment considerations:

- Supplement cofactors (B1, B2, B3, B5, Mg, cysteine or lipoic acid)
- Remove toxic metals (As, Hg, Sb, Cd)
- Antifungals, anti-yeast diet
- Probiotics if relevant

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