Formiminoglutamic Acid (FIGlu) is a functional marker of insufficiency of folic acid, another B-vitamin, and is a compound made from the amino acid histidine.
Pregnant women especially need to have adequate folic acid to prevent birth defects. Folic acid insufficiency can play a role in childhood development problems, depression, immune function, and is a risk factor for cardiovascular disease.
Insufficiency of folic acid leads to high urinary Formiminoglutamic Acid.
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High levels can indicate:
- insufficient folic acid
- increased alcohol consumption
- excessive consumption of processed foods
- oral contraception
Smoking and pregnancy will all have a detrimental impact on folic acid absorption.
Symptoms:
Common symptoms may include:
- anemia
- fatigue
- elevated homocysteine
- ischemic heart disease
- stroke
- deep vein thrombosis.
Pregnant women especially need to have adequate folic acid to prevent birth defects.
Folic acid insufficiency can play a role in:
- childhood development problems
- depression
- immune function
Folic acid insufficiency is a risk factor for cardiovascular disease.
Possible treatment options if high:
- consider supplementing with folic acid.
- stop consumption of alcohol.
- if homocysteine is elevated, consider using 5-methyltetrahydrofolate.
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2-Hydroxyphenylacetic Acid, 3-Hydroxyisovaleric Acid, 3-Hydroxyphenylacetic Acid, 3-Hydroxypropionic Acid, 3-Methyl-4-OH-phenylglycol, 4-Hydroxyphenylacetic Acid, 5-OH-indoleacetic Acid, a-Hydroxyisobutyric Acid (from MTBE), a-Keto-b-Methylvaleric Acid, a-Ketoadipic Acid, a-Ketoglutaric Acid (AKG), a-Ketoisocaproic Acid, a-Ketoisovaleric Acid, a-Ketophenylacetic Acid (from Styrene), Adipic Acid, Arabinose, B-OH-B-Methylglutaric Acid (HMG), Benzoic Acid, Beta-OH-Butyric Acid (BHBA), Cis-Aconitic Acid, Citramalic Acid, Citric Acid, Dihydroxyphenylpropionic Acid (DHPPA), Formiminoglutamic Acid (FIGlu), Glutaric Acid, Hippuric Acid, Homogentisic Acid, Homovanillic Acid, Indoleacetic Acid (IAA), Isocitric Acid, Isovalerylglycine, Kynurenic / Quinolinic Ratio, Kynurenic Acid, Lactic Acid, Malic Acid, Methylmalonic Acid, Orotic Acid, Phenylacetic Acid (PAA), Pyroglutamic Acid, Pyruvic Acid, Quinolinic Acid, Suberic Acid, Succinic Acid, Tartaric Acid, Vanilmandelic Acid, Xanthurenic Acid
