3-Methyl-4-OH-phenylglycol is the breakdown product from norepinephrine, but it may also be produced from epinephrine to a lesser extent.
Possible causes:
- Low precursors/neurotransmitters (phenylalanine, dopamine, noradrenalin)
- Low cofactors (B2, B3, B6, Mg or Fe)
- Impaired methylation (if VMA also low)
Additional investigations:
- Vitamins & Minerals Analysis
Treatment considerations:
- L-tyrosine & B6
- Support methylation (methionine or SAMe, B6, B12, folate, Mg)
Increase catecholamine activity stress pattern OR pheochromocytoma OR possible deficient CNS dopamine receptors.
Possible causes:
- Increased catecholamine activity/stress pattern
- Possible deficient CNS dopamine receptors
Additional investigations:
- Adrenal Hormone Profile
Treatment considerations:
- Adrenal support
- Stress management
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2-Hydroxyphenylacetic Acid, 3-Hydroxyisovaleric Acid, 3-Hydroxyphenylacetic Acid, 3-Hydroxypropionic Acid, 3-Methyl-4-OH-phenylglycol, 4-Hydroxyphenylacetic Acid, 5-OH-indoleacetic Acid, a-Hydroxyisobutyric Acid (from MTBE), a-Keto-b-Methylvaleric Acid, a-Ketoadipic Acid, a-Ketoglutaric Acid (AKG), a-Ketoisocaproic Acid, a-Ketoisovaleric Acid, a-Ketophenylacetic Acid (from Styrene), Adipic Acid, Arabinose, B-OH-B-Methylglutaric Acid (HMG), Benzoic Acid, Beta-OH-Butyric Acid (BHBA), Cis-Aconitic Acid, Citramalic Acid, Citric Acid, Dihydroxyphenylpropionic Acid (DHPPA), Formiminoglutamic Acid (FIGlu), Glutaric Acid, Hippuric Acid, Homogentisic Acid, Homovanillic Acid, Indoleacetic Acid (IAA), Isocitric Acid, Isovalerylglycine, Kynurenic / Quinolinic Ratio, Kynurenic Acid, Lactic Acid, Malic Acid, Methylmalonic Acid, Orotic Acid, Phenylacetic Acid (PAA), Pyroglutamic Acid, Pyruvic Acid, Quinolinic Acid, Suberic Acid, Succinic Acid, Tartaric Acid, Vanilmandelic Acid, Xanthurenic Acid
