GI360 stool profile / Doctor's Data

Faecalibacterium prausnitzii

Optimal Result: 0 - 0 Units.

Faecalibacterium prausnitzii is one of the most abundant butyrate producing bacteria in a healthy gastrointestinal tract. As such, F. prausnitzii is a protective factor for the intestinal mucosa and supports very important intestinal barrier functions. F. prausnitzii exerts anti-inflammatory effects via metabolites such as short-chain fatty acids. F. prausnitzii is reduced in inflammatory bowel disease, irritable bowel syndrome, celiac disease and gastrointestinal inflammation in general. It is reduced in patients diagnosed with Parkinson’s disease, bipolar disorder, colorectal cancer, diabetes and chronic idiopathic diarrhea. Diminished levels of F. prausnitzii were found in patients with major depressive disorder. The abundance of F. prausnitzii together with E. coli (F-E index) has been proposed as a discrimination tool between ulcerative colitis and Crohn’s disease. F. prausnitzii has been correlated with pediatric obesity in instances of high consumption of foods that are rich in unabsorbed carbohydrate (banana, maize, rice). The prebiotic inulin has been shown to increase the proportion of F. prausnitzii in the human intestinal microbiota. Low FODMAP diets have been observed to reduce the abundance of F. prausnitzii and butyrate production.

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