Rotaviruses are classified into seven serogroups (A-G); however, only groups A, B, and C are human pathogens.
The Group A Rotaviruses are responsible for the majority of infections.
Globally, Rotavirus is estimated to cause more than 125 million cases of gastroenteritis in children each year. Rotavirus symptoms can include non-bloody watery diarrhea, loss of appetite, low-grade fever, vomiting and abdominal cramping. Symptoms may be severe in infants, young children and virus may shed after resolution. While Rotavirus predominately infects children, it can also affect adults, and produces a more severe disease in immuno-compromised hosts. Transmission is via direct contact or fecal-oral via contaminated objects, food or water (drinking or recreational). Incubation period is typically two days and virus may shed prior to symptom presentation. Anti-emetics may be considered for children > 6 months old. Studies indicate that zinc may reduce severity of illness. The scientific literature does not currently support any specific herbal or nutritional antiviral therapies for this virus type. Lactobacillus casei GG and Saccharomyces boulardii may provide moderate clinical benefit in the treatment of watery diarrhea.
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