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Members of Ruminococcus sensu produce acetate, but not butyrate.

Ruminococcus gnavus, like Akkermanisia muciniphila is a mucin degrading specialist. 

Higher levels of Ruminococcus spp. were associated with non-alcoholic fatty liver disease and non-alcoholic steatohepatitis. 

Increased abundance of Ruminococcus spp. has been reported in irritable bowel syndrome (IBS), whereas Ruminococcus spp. are reportedly decreased in abundance with Crohn's disease and ulcerative colitis. Ruminococcus gnavus has been found to be in higher abundance in diarrhea predominant IBS. Intake of resistant starch has been associated with increased levels of R. bromii, whereas a diet rich in animal protein and fat was found to reduce the abundance of this species in human gut.

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