Beta defensin 2 is an antibiotic peptide locally regulated by inflammation in humans. It is produced by a number of epithelial cells and exhibits potent antimicrobial activity against Gram-negative bacteria and Candida, but not Gram-positive bacteria. It has been speculated that beta-defensin 2 may contribute to the infrequency of Gram-negative infections on skin and lung tissue.
References:
Elevated Human [beta]-Defensin-2 Levels Indicate an Activation of the Innate Immune System in Patients With Irritable Bowel Syndrome
Langhorst, Jost; Junge, Angela; Rueffer, Andreas; Wehkamp, Jan; Foell, Dirk; et al. The American Journal of Gastroenterology; New York Vol. 104, Iss. 2, (Feb 2009): 404-410. [L]
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Elevated human beta-defensin-2 levels indicate an activation of the innate immune system in patients with irritable bowel syndrome. [L] Consider broad spectrum probiotics to improve gut diversity along with probiotic foods.
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Acetate, Akkermansia muciniphila, Beta defensin 2, Bifidobacterium, Bifidobacterium longum, Butyrate, Butyrivibrio, Calprotectin, Chenodeoxycholic acid (CDCA), Cholic acid (CA), Deoxycholic acid (DCA), Enterobacteriaceae, Eubacterium, Eubacterium rectale, Faecalibacterium prausnitzii, Fecal Anti Gliadin, Fecal Eosinophil Protein X, Fecal lactoferrin, Fecal Occult Blood, Fecal pH, Fecal Zonulin, Lactobacillus, Lactobacillus acidophilus, Lactobacillus bulgaricus, Lactobacillus plantarum, Lactobacillus reuteri, Lactobacillus rhamnosus, LCA/DCA ratio, Lithocholic acid (LCA), Long chain fatty acids, Lysozyme, Meat Fiber, MMP 9, Pancreatic elastase 1, Propionate, Propionibacterium, Roseburia, S100A12, sIgA, Streptococcus species, Streptococcus thermophilus, Total Cholesterol, Total Cholesterol subfraction, Total Fecal Fat, Total Fecal Triglycerides, Total Phospholipid subfraction, Total Short chain fatty acids, Valerate, Vegetable fiber, ß-glucuronidase
