Lactobacillus rhamnosus was first isolated in 1983 and is known to have a strong avidity for human intestinal cells and can survive acid and bile environments. It is considered one of the most studied probiotics, with research showing that it could do the following:
- alleviate rotavirus diarrhea in children,
- prevent atopic dermatitis,
- protect against urinary tract infections,
- and improve symptoms of irritable bowel syndrome.
Lactobacillus rhamnosus appears to be safe and effective in prolonging remission in UC patients. LGG has also been studied in CD, but found to be no better than placebo.
References:
Inflammatory Bowel Disease. / Parian, Alyssa M.; Mullin, Gerard E.; Langhorst, Jost; Brown, Amy C., Integrative Medicine: Fourth Edition. Elsevier, 2018.
When Lactobacillus and other anaerobic bacteria levels are low, like in IBD patients, the gut loses anti-inflammatory features that exist in healthy individuals and the disease flares up.
Probiotics can help to restore the gut homeostasis. There is a lot of research which shows probiotics, like Bifidobacteria and Lactobacilli, can help control gut inflammation and improve IBD.
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Acetate, Acinetobacter, Akkermansia muciniphila, b-glucuronidase producing bacteria, Bacteroides, Bacteroides vulgatus, Beta defensin 2, Bifidobacterium, Bifidobacterium animalis, Bifidobacterium animalis subspecies lactis, Bifidobacterium dentium, Bifidobacterium infantis, Bifidobacterium longum, Blautia, Bradyrhizobiaceae, Butyrate, Butyricimonas, Butyrivibrio, Calprotectin, Catenibacterium, Chenodeoxycholic acid (CDCA), Cholic acid (CA), Christensenella minuta, Clostridia clusters XIVa, Clostridiales Family XIV Incertae Sedis, Clostridium, Clostridium hathewayi, Clostridium ramosum, Clostridium symbiosum, Clotridiales Incertae Sedis IV, Collinsella, Coprococcus, Deoxycholic acid (DCA), Desulfovibrio, Desulfovibrio piger, Eggerthella lenta, Enterobacteriaceae, Enterococcus species, Enterotoxigenic E.coli (ETEC) Lt/St, Escherichia coli, Eubacterium, Eubacterium rectale, Faecalibacterium prausnitzii, Fecal Anti Gliadin, Fecal Eosinophil Protein X, Fecal lactoferrin, Fecal Occult Blood, Fecal pH, Fecal Zonulin, Fusobacterium, Lactobacillaceae, Lactobacillus, Lactobacillus acidophilus, Lactobacillus animalis, Lactobacillus brevis, Lactobacillus bulgaricus, Lactobacillus casei, Lactobacillus fermentum, Lactobacillus plantarum, Lactobacillus reuteri, Lactobacillus rhamnosus, Lactobacillus ruminis, LCA/DCA ratio, Leuconostoc, Lithocholic acid (LCA), Long chain fatty acids, Lysozyme, Meat Fiber, Methanobrevibacter smithii, Micrococcus, MMP 9, Pancreatic elastase 1, Peptostreptococcus, Phascolarctobacterium, Prevotella, Prevotella copri, Propionate, Propionibacterium, Propionibacterium freudenreichii, Proteus mirabilis, Roseburia, Ruminococcus obeum, S100A12, Sapovirus I, Sapovirus V, sIgA, Solobacterium moorei, Staphylococcaceae, Staphylococcus epidermidis, Staphylococcus species, Streptococcus species, Streptococcus thermophilus, Total Cholesterol, Total Cholesterol subfraction, Total Fecal Fat, Total Fecal Triglycerides, Total Phospholipid subfraction, Total Phospholipids, Total Short chain fatty acids, Tyzzerella, Tyzzerella 4, Valerate, Vegetable fiber, ß-glucuronidase