BLOOD - Red Cell
Optimal Result: 1 - 2 ug/L.

Chromium is ubiquitous in foods at low low concentrations. Derived from processing of food with stainless steel equipment. Also present in tobacco smoke, chrome, plating, dyes and pigments, leather tanning, and wood preserving and is deposited into air, water, and soil.

Blood distribution of chromium appears to be equally divided between plasma and RBCs, whole blood chromium the sample type for total chromium measurement. Chromium (VI) is more concentrated in the RBCs, while chromium (III) does not enter the RBCs. Therefore, it is possible to distinguish sources and types of exposure to indicate toxic  (Cr VI) exposure versus benign (Cr III) by measuring RBC chromium. Chromium rapidly clears from the blood and measurements relate to recent exposure. Urinary chromium excretion reflects absorption of the previous one to two days.

Chromium is often given as a supplement to treat glucose intolerance by improving insulin sensitivity.

→ There is debate as to whether chromium is an essential trace element.

→ Hip prosthesis, bearing surfaces are made from cobalt and other materials, including chromium.

→ Welding produces fumes that may contain chromium and other metals (Mn, As, Fe, Ni).

→ Dietary chromium absorption is low.

→ Chromium is bound to the protein transferring in the bloodstream.

→ Conditions that increase circulating glucose and insulin increase urinary chromium output.

Symptoms of imbalance:

Currently, no symptoms of chromium deficiency exist. Compounds containing hexavalent chromium (chromium VI) are mutagenic and carcinogenic in large quantities. No adverse effects have been associated with trivalent chromium (chromium III), the form and food and supplements. Inhaled chromium may cause irritation to the lining of the nose, nose, ulcers, runny nose, and breathing proble, asthma, cough, shortness of breath, or wheezing. Dermal contact with chromium, make her skin, ulcers, redness, and swelling. Ingested, chromium and brackets in animals may cause irritation, and ulcers in the stomach and small intestine and anemia.

The FDA recommends testing chromium in whole blood in patients with metal on metal hip implants who have symptoms. These symptoms may include localized pain due to damage bone and/or tissue surrounding the implant and joint.

What does it mean if your Chromium result is too high?

Elevated levels of chromium can indicate a few potential issues. Chromium is a trace mineral that plays a crucial role in regulating blood sugar by enhancing the action of insulin. High levels of chromium might suggest over-supplementation or excessive dietary intake, which can occur from taking too many chromium supplements or consuming large amounts of chromium-rich foods. Additionally, it might indicate environmental exposure, as chromium can be found in certain industrial settings and contaminated water sources. Chronic high levels of chromium can potentially lead to toxicity, manifesting in symptoms like gastrointestinal distress, liver and kidney damage, or dermatitis. However, mild elevations might simply reflect dietary habits without serious health implications. It is important to interpret these results in the context of overall health, dietary intake, and potential environmental exposures, often requiring consultation with a healthcare professional to determine the appropriate action.

What does it mean if your Chromium result is too low?

Currently, no symptoms of chromium deficiency exist. Compounds containing hexavalent chromium (chromium VI) are mutagenic and carcinogenic in large quantities. No adverse effects have been associated with trivalent chromium (chromium III), the form and food and supplements. Inhaled chromium may cause irritation to the lining of the nose, nose, ulcers, runny nose, and breathing proble, asthma, cough, shortness of breath, or wheezing. Dermal contact with chromium, make her skin, ulcers, redness, and swelling. Ingested, chromium and brackets in animals may cause irritation, and ulcers in the stomach and small intestine and anemia.


Low chromium levels on a Metabolomix+ panel from Genova Diagnostics could indicate a deficiency of chromium in your body. Chromium is an essential trace mineral that plays a role in various metabolic processes, including glucose metabolism. Here are some potential implications of low chromium levels:

→ Impaired glucose regulation: Chromium is known to enhance the action of insulin, a hormone that helps regulate blood sugar levels. Low chromium levels may lead to poor insulin sensitivity and difficulty in controlling blood sugar levels, potentially increasing the risk of insulin resistance and type 2 diabetes.

→ Increased risk of cardiovascular disease: Chromium deficiency has been associated with an increased risk of cardiovascular disease. Chromium helps maintain healthy cholesterol levels and supports the proper function of blood vessels.

→ Impaired energy metabolism: Chromium is involved in the metabolism of carbohydrates, fats, and proteins. Low chromium levels may affect your body's ability to efficiently convert these macronutrients into energy, potentially leading to fatigue and reduced physical performance.

→ Weight management: Some studies have suggested that chromium supplementation may help with weight management and reducing food cravings. Low chromium levels could potentially lead to difficulties in controlling appetite and body weight.

It's important to note that low chromium levels may be influenced by various factors, including dietary habits, genetics, and underlying health conditions. If your Metabolomix+ panel indicates low chromium levels, it is essential to discuss the results with a healthcare provider or a registered dietitian. They can help you determine the underlying cause of the deficiency and develop an appropriate plan for supplementation or dietary changes if necessary.

Frequently asked questions

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