Also known as: Alpha-Amino-N-Butyric Acid to Leucine ratio
Alcohol consumption can result in elevations of the plasma Alpha-ANB/Leucine ratio. But to see this biomarker as a conclusive marker for alcoholism is not proven. The increase in the plasma Alpha-ANB/Leucine ratio does not appear to be specific for alcoholism because it was found elevated in nonalcoholic liver disease.
It is most likely that the rise in the plasma Alpha-ANB/Leucine ratio identifies a subgroup of alcoholics. What determines this subgroup of alcoholics remains unclear, but it could be the quantity of alcohol intake, a nutritional deficiency, or the presence of liver disease.
References:
- Plasma alpha-amino-n-butyric acid/leucine ratio in alcoholics. (L)
- On the clinical significance of the plasma alpha-amino-n-butyric acid:leucine ratio. (L)
- Plasma alpha amino-n-butyric acid to leucine ratio: an empirical biochemical marker of alcoholism (L)
- Ratio of plasma α-amino-n-butyric acid to leucine in alcoholism (L)
a-Amino-n-Butyrate/Leucine
Every lab result you’ve ever had, charted and explained.
Healthmatters is a tracker for your lab results. Upload a report from any lab, any country — every marker charted and explained.
Start with my report →
All our content is backed by peer-reviewed studies, academic research, and trusted medical sources. We’re committed to accuracy and transparency — see our editorial policy for details.