Optimal Result: 264 - 916 ng/dL, 9.16 - 31.79 nmol/L, or 2.64 - 9.16 ng/mL.

This test assesses the level of the hormone testosterone in your bloodstream. Testosterone, an androgen, is primarily responsible for the development of male characteristics. It is synthesized in the testes for males, ovaries for females, and the adrenal glands.

During puberty in males, testosterone induces several changes, including the growth of hair, muscles, penis, and testes, along with a deepening of the voice. It continues to be produced in adult males, promoting sex drive and aiding in sperm maturation.

Females also produce small amounts of testosterone in their ovaries, contributing to various bodily functions.

The pituitary gland in the brain regulates testosterone production by releasing signaling hormones such as luteinizing hormone.

Most of the testosterone in the blood binds to two proteins: albumin and sex hormone binding globulin (SHBG). Some remains unbound, known as free testosterone, which is easily utilized by the body. This unbound form, along with albumin-bound testosterone, is termed bioavailable testosterone.

In the assessment of testosterone levels by healthcare providers, total testosterone levels are initially tested, encompassing all three types. Free testosterone measurements can provide additional information when total testosterone levels are low.

Both males and females can experience health issues due to low or high testosterone levels. High testosterone in females may lead to conditions like polycystic ovary syndrome (PCOS), resulting in infertility, irregular menstruation, acne, obesity, blood sugar problems, and excessive facial hair growth.

As males age, testosterone levels typically decline, but this natural decrease is not considered hypogonadism. The FDA currently advises against treating age-related low testosterone in males.




What does it mean if your Testosterone result is too high?

Abnormally high testosterone levels are also known as hypergonadism.

Possible signs and symptoms of high testosterone include:

- Acne

- Aggression

- Early puberty, in young men

- Excessive “hairiness”

- High blood pressure

- High libido

- High red blood cell count

- Increased risk-taking behaviors

- Infertility and decreased sperm count

Abnormally high testosterone levels can be caused by:

Tumors: Adrenal and testicular tumors may cause abnormally high testosterone.

Anabolic steroid abuse: Sometimes used by athletes and bodybuilders to build more muscle mass or increase athletic performance. Some athletes take Clomid illegally to boost performance. 

Testosterone supplementation: Sometimes prescribed by a physician, and sometimes purchased illegally without a prescription.

Testosterone gel: Coming into contact with someone who is using testosterone gel can be an issues. The gel can accidentally be rubbed off onto someone else, raising their testosterone levels unintentionally.

Lowering high testosterone levels in men can be achieved through dietary and lifestyle changes. Here are some effective strategies:

→ Dietary Adjustments:

- Reduce consumption of foods high in saturated fats and processed sugars, as they can increase testosterone levels.

- Avoid or limit soy products, dairy, and alcohol, as they may lower testosterone levels.

- Incorporate foods like flaxseed and soy products into your diet, as they can help reduce testosterone production.

→ Lifestyle Changes:

- Maintain a healthy weight through regular exercise, as obesity is linked to higher testosterone levels.

- Manage stress levels through relaxation techniques, as chronic stress can raise testosterone levels.

→ Medications and Hormone Therapy:

- Consult with a healthcare professional about hormone-based birth control or androgen blockers if necessary.

It's important to note that these methods should be discussed with a healthcare provider to determine the most appropriate approach based on individual health needs.

What does it mean if your Testosterone result is too low?

Potential symptoms of low testosterone in males include:

- Large breasts

- Low sex drive or lack of interest in sex

- Trouble getting an erection

- Low sperm count and other fertility problems

- Changes in the testicles

- Weak bones

- Irritability

- Trouble concentrating

- Loss of muscle mass

- Hair loss

- Depression

- Fatigue

- Anemia

Potential causes of low testosterone in men:

Age: Once men reach age 50, testosterone levels begin a natural decline. Male fertility does decline with age, though not as drastically as it does in women.

Obesity: Obesity may have an even bigger impact on testosterone levels than age. Research has found that increases in weight are directly related to lowering testosterone levels. Losing weight can bring your testosterone levels back up.

Smoking: Smoking also increases your risk of male infertility.

Being underweight: Abnormally low weight, malnutrition, and excessive exercise can lead to low testosterone levels and decreased fertility.

Klinefelter syndrome (KS): This is a genetic disorder where instead of having one X and one Y chromosome, the man has an additional X chromosome. It is a common cause of male infertility.

Kallmann syndrome: This is a genetic condition where puberty either fails to begin or doesn’t complete.

Pituitary disorders: This includes problems with how the pituitary functions. It may be the result of a pituitary tumor or brain tumor. Or, treatment of a brain tumor with radiation can cause long-term damage to the pituitary.

Undescended testicles: This usually resolves during early childhood. If not, though, it must be corrected. Otherwise, it can cause hormonal problems later in life.

Abnormally high levels of iron: This is also known as hemochromatosis.

Testicular injury: If just one testicular is injured, testosterone production may be normal.

Cancer treatment: Chemotherapy and radiation therapy can temporarily cause low testosterone and impair sperm production. However, sometimes the damage is permanent. One study found that 30 percent of men experienced low testosterone levels after treatment.

HIV/AIDS: the virus can interfere with how the testes, pituitary, and hypothalamus function. This, in turn, can lead to low testosterone levels.

Major illness or surgery: This will usually reverse itself after recovery time. Some infections, like mumps, can cause long-term hormonal problems.

Medical or recreational drug use: For example, marijuana can cause lower testosterone levels.

Extremely high levels of stress: High levels of the stress hormone cortisol have been associated with lower levels of testosterone.

Boosting low testosterone in men can be achieved through various natural methods:

→ Dietary Improvements: Maintain a healthy diet rich in nutrients. This includes consuming adequate protein, healthy fats, and carbohydrates.

→ Regular Exercise: Engage in both cardiovascular and resistance training exercises. Weightlifting, in particular, can help boost testosterone levels.

→ Stress Management: High stress levels can contribute to low testosterone. Employ stress-reduction techniques such as meditation, yoga, or deep breathing exercises.

→ Adequate Sleep: Ensure you get enough quality sleep each night, as sleep is crucial for hormone regulation.

→ Maintain a Healthy Weight: Losing excess body fat can help improve testosterone levels, as obesity is linked to lower testosterone.

→ Nutritional Supplements: Consider supplements like zinc and vitamin D, which are known to support testosterone production.

→ Include Testosterone-Boosting Foods: Incorporate foods such as ginger, oysters, pomegranates, leafy green vegetables, and fatty fish into your diet to naturally support testosterone levels.

Always consult with a healthcare professional before making significant lifestyle changes or taking supplements, especially if you suspect you have low testosterone levels. They can provide personalized guidance and determine the most suitable approach for your specific situation.


What if your FSH and LH are also low?

Low levels of testosterone, follicle-stimulating hormone (FSH), and luteinizing hormone (LH) in a male typically indicate a condition related to the dysfunction of the hypothalamic-pituitary-gonadal (HPG) axis. This axis is a complex set of hormone interactions that regulates the production of testosterone and other sex hormones.

When both FSH and LH are low, it suggests a problem with the pituitary gland or hypothalamus, rather than the testes themselves. This condition is often referred to as secondary hypogonadism or hypogonadotropic hypogonadism. It can be caused by various factors, including:

  1. Pituitary Disorders: Tumors, such as prolactinomas, or other pituitary gland abnormalities can impair hormone production.
  2. Hypothalamic Disorders: Issues with the hypothalamus, such as tumors, trauma, or congenital conditions like Kallmann syndrome, can affect the release of gonadotropin-releasing hormone (GnRH), which in turn influences FSH and LH production.
  3. Chronic Illness or Stress: Prolonged illness or significant physical or psychological stress can suppress the HPG axis.
  4. Medications: Certain medications, such as opioids or glucocorticoids, can interfere with hormone production.
  5. Obesity: Excess body fat can affect hormone levels and disrupt the normal functioning of the HPG axis.

Low testosterone levels can lead to a variety of symptoms, including decreased libido, erectile dysfunction, fatigue, depression, reduced muscle mass and strength, and increased body fat.

Diagnosis typically involves blood tests to measure hormone levels, along with imaging studies like MRI to examine the pituitary gland. Treatment depends on the underlying cause but may include hormone replacement therapy, medications to stimulate hormone production, or addressing the primary condition affecting the hypothalamus or pituitary gland. Lifestyle changes, such as weight loss, stress management, and proper nutrition, can also help improve hormone levels and overall health. Consulting an endocrinologist or a healthcare provider specializing in hormone disorders is essential for a proper diagnosis and treatment plan.

Frequently asked questions

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