A healthy result should fall into the range 0 - 0.5 nmol/L.
Glutamic acid decarboxylase is an enzyme found in brain and pancreas that converts glutamic acid (glutamate) into GABA, an inhibitory neurotransmitter. The glutamic acid decarboxylase test is a test that looks for antibodies directed against the glutamic acid decarboxylase enzyme. While glutamic acid decarboxylase is a critical enzyme in brain, it is also found in beta cells in the pancreas. Some individuals develop autoantibodies against glutamic acid decarboxylase. When these antibodies are detectable in the blood, they may represent an autoimmune disease. The test is performed using radioimmunoassay. The absence or very low levels of glutamic acid decarboxylase autoantibodies are considered normal. Less than 10% of healthy individuals will have low levels of glutamic acid decarboxylase antibodies, suggesting that they may be present in people without disease.
Normal Ranges for Glutamic Acid Decarboxylase:
Less than or equal to 0.02 nmol/L
insert the value from you Glutamic Acid Decarboxylase test result.
It is not possible to have glutamic acid decarboxylase antibody levels that are too low.
The two main types of diseases in which glutamic acid decarboxylase autoantibodies are present are diabetes and neurological disease. Approximately 4 out of 5 people with type I diabetes will have low levels of these autoantibodies. On the other hand, less than 5% of people with type II diabetes will have detectable amounts of these autoantibodies in their serum. The presence of these autoantibodies does not necessarily diagnose particular neurological diseases; however, a portion of people with various autoimmune neurological disorders will have low titers of glutamic acid decarboxylase antibodies. These antibodies may also predict a predisposition to certain autoimmune diseases such as autoimmune thyroid disease, pernicious anemia, Addison disease, and vitiligo.
Some specific causes of glutamic acid decarboxylase antibodies are:
$15 one time
$59 per year
Health is not exactly rocket science. You just have to know what your body needs and doesn't need. Your medical tests contain that information. Upload them to our service and we’ll help you understand organize, and act on them.Get Started
"I was really concerned about my lab results and my GP was not able to see me for another week. Through HealthMatters I was able to interpret my results instantly."
"I've been keeping all my lab results in a spreadsheet, covering approximately 20 years. The HealthMatters team helped me upload that info into the cloud. I can show this data to my family and doctors now easily."
"I had no idea what my lab results meant. Here I found all the biomarkers that I was looking for online. Finally, I have not only organized them all neatly in one place, but I am also grateful to be able to understand what they mean."