The anti-insulin antibody test checks to see if your body has produced antibodies against insulin.
Antibodies are proteins the body produces to protect itself when it detects anything "foreign," such as a virus or transplanted organ.
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If you have antibodies against insulin, your body reacts as if the insulin in your body is a foreign protein that needs to be removed. This result can be part of the testing that diagnoses you with autoimmune or type 1 diabetes.
If you have diabetes and develop anti-insulin antibodies, this may make insulin less effective, or not effective at all.
This is because the antibody prevents the insulin from working the right way in your cells. As a result, your blood sugar can be unusually high. Many people who are taking insulin to treat their diabetes have detectable antibodies. However, these antibodies do not cause symptoms or change the effectiveness of insulin.
The antibodies can also prolong the effect of insulin by releasing some insulin long after your meal has been absorbed. This can put you at risk for low blood sugar.
Other medicines, such as antihistamines or low-dose injectable steroids, may help to lessen the reaction. If reactions have been severe, you may need a treatment process called desensitization or another treatment to remove the antibodies from your blood.
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1,5-Anhydroglucitol (1,5-AG), Intermediate Glycemic Control, 5-Methyltetrahydrofolate, Adiponectin, Albumin/Creatinine Ratio, Random Urine, Anti-Thyroglobulin ab. (0-39), C-Peptide, LC/MS/MS, C-Peptide, Serum, C-Peptide, Ultrasensitive (Endocrine Sciences), Ceruloplasmin, Creatinine, Random Urine, Cyclic AMP, Plasma, Dihydrotestosterone (female), Dihydrotestosterone (male), Estimated Average Glucose (eAG), Free Androgen Index, Free testosterone, Free Testosterone (Male) in pmol/L, Free Testosterone (Male/Serum) in ng/ml, Free Testosterone, Direct (Female), Free Testosterone, Direct (Male), Free Testosterone, Percent (Female), Fructosamine, Glutamic Acid Decarboxylase, Glycated Serum Protein (GSP), Hemoglobin A1c (HbA1c), HOMA-B, HOMA-IR, HOMA-S, Homocysteine, Insulin (Fasting), Insulin Antibody, Insulin Resistance Score, Insulin, Intact, LC/MS/MS, Insulin-Like Growth Factor I (IGF-1), Iodine, Serum/Plasma, Nonesterified Fatty Acids (Free Fatty Acids), Pregnenolone, Proinsulin, Sex Hormone-Binding Globulin (SHBG), T7 Index, Testost., % Free+Weakly Bound, Testost., % Free+Weakly Bound (female), Testost., F+W Bound (female), Testosterone, Testosterone (Female/Child), Testosterone, bioavailable, Testosterone, bioavailable (male), Testosterone, Serum (Female), Thyroglobulin, Thyroglobulin Antibodies (0 - 1 IU/L), Thyrotropin Receptor Ab, Serum, Thyroxine-binding globulin, TBG, TMAO (Trimethylamine N-oxide), Triiodothyronine, Serum, TSH Receptor Antibody (TBII), Zinc Transporter 8 (ZnT8) Antibody