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Optimal range: 68 - 114 mg/dL , 3.77 - 6.33 mmol/L
Your estimated Average Glucose (eAG) number is calculated from the result of your A1c test. Like the A1c, the eAG shows what your average blood sugars have been over the previous 2 to 3 months, but instead of a percentage, the eAG is in the same units (mg/dl) as your blood glucose meter.
Optimal range: 0 - 1 times avg.
The CHD Risk is based on the T. Chol/HDL ratio. Other factors affect CHD Risk such as hypertension, smoking, diabetes, severe obesity, and family history of premature CHD.
Optimal range: 45.4 - 1461 pmol/L , 12.37 - 397.98 pg/mL
Estradiol (Estrogen) is a female hormone, produced primarily in the ovary. The amount of estrogen produced depends on the phase of the menstrual cycle.
Men also produce estradiol, but only very small amounts.
Shortly before ovulation, estradiol levels surge and then fall immediately after ovulation. They then rise again and remain elevated until 2-3 days before menstruation.
Optimal range: 0.8 - 3.3 ng/mg CR
Estradiol (E2) is critical for assessing the estrogenic activity and hormonal balance in women. Estradiol, the most potent of the three major estrogens (which also include estrone and estriol), plays a pivotal role in female reproductive health, influencing the menstrual cycle, fertility, and secondary sexual characteristics.
Estradiol is primarily produced by the ovaries in premenopausal women and, to a lesser extent, by adipose tissue and the adrenal glands. Its production is stimulated by follicle-stimulating hormone (FSH) and luteinizing hormone (LH). In postmenopausal women, estradiol levels significantly decrease due to diminished ovarian function, with a relative increase in the importance of peripheral sources like adipose tissue for its production.
Optimal range: 0.78 - 1.79 µg/g creatinine
The most physiologically active estrogen. Binds to both to ER and Estrogen Receptor Beta (ERβ). Estradiol, made in the ovary, rapidly converts to estrone. Poor symptom control with estrogen replacement may suggest the need for improving absorption or increasing estradiol.
Optimal range: 1.8 - 4.5 ng/mg
The most physiologically active estrogen. Binds to both to ER and Estrogen Receptor Beta (ERβ). Estradiol, made in the ovary, rapidly converts to estrone. Poor symptom control with estrogen replacement may suggest the need for improving absorption or increasing estradiol.
Optimal range: 2.9 - 13.7 pmol/L
Estrogens play a critical role in female sexual development, menstrual function, protein synthesis, cardiovascular function, bone formation and remodeling, cognitive function, emotional balance and other important health factors. The estrogenic potency of estradiol is 12 times that of estrone and 80 times that of estriol. Estradiol is the primary estrogen in premenopausal women. Estrone is the second most potent estrogen compared to estradiol.
Optimal range: 0.6 - 4.5 pg/mL
Estradiol (E2) is produced in women mainly in the ovary. The testes and adrenal glands are the principal source of estradiol in men. In women, normal levels of estradiol provide for proper ovulation, conception, and pregnancy, while also promoting healthy bone structure and regulating cholesterol levels.
Optimal range: 1.6 - 6.6 ug/g Creatinine
The most physiologically active estrogen. Binds to both to ER and Estrogen Receptor Beta (ERβ). Estradiol, made in the ovary, rapidly converts to estrone. Poor symptom control with estrogen replacement may suggest the need for improving absorption or increasing estradiol.
Optimal range: 0.6 - 11.2 mcg/g Creat.
The most physiologically active estrogen. Binds to both to ER and Estrogen Receptor Beta (ERβ). Estradiol, made in the ovary, rapidly converts to estrone. Poor symptom control with estrogen replacement may suggest the need for improving absorption or increasing estradiol.
Optimal range: 0.5 - 2.2 ng/mg
Estradiol is the main "female" hormone. The full name is 17-beta-Estradiol.
Current research indicates that, in some people, this hormone may play a role in the loss of bone density, prevents male bodies from clearing DHT out of the prostate gland, and can stimulate estrogen-sensitive tumor growth (if estrogen-sensitive cancer cells are already present).
Optimal range: 0.6 - 11.2 mcg/g Creat.
The most physiologically active estrogen. Binds to both to ER and Estrogen Receptor Beta (ERβ). Estradiol, made in the ovary, rapidly converts to estrone. Poor symptom control with estrogen replacement may suggest the need for improving absorption or increasing estradiol.
Optimal range: 0.2 - 0.7 ng/mg
The most physiologically active estrogen. Binds to both to ER and Estrogen Receptor Beta (ERβ). Estradiol, made in the ovary, rapidly converts to estrone. Poor symptom control with estrogen replacement may suggest the need for improving absorption or increasing estradiol.
Optimal range: 0.6 - 15.4 mcg/g Creat.
The most physiologically active estrogen. Binds to both to ER and Estrogen Receptor Beta (ERβ). Estradiol, made in the ovary, rapidly converts to estrone. Poor symptom control with estrogen replacement may suggest the need for improving absorption or increasing estradiol.
Optimal range: 0.4 - 2 ng/mg Creat/Day
Estradiol level is most consistent with exogenous exposure, supplementation, or aromatization of testosterone to estradiol. CYP19, also known as aromatase, can be upregulated raising intracellular estrogens in men which can contribute to increased adiposity, metabolic syndrome, and prostate pathology. CYP19 enzyme is induced during times of stress, exposure to xeno-estrogens, high glycemic diet, excessive adipose tissue, and alcohol consumption.
Optimal range: 7.6 - 42.6 pg/mL , 27.90 - 156.40 pmol/L
Estradiol is the main "female" hormone. The full name is 17-beta-Estradiol.
Current research indicates that, in some people, this hormone may play a role in the loss of bone density, prevents male bodies from clearing DHT out of the prostate gland, and can stimulate estrogen-sensitive tumor growth (if estrogen-sensitive cancer cells are already present).
Men need to produce estrogen through a process involving an enzyme called aromatase that transforms testosterone into estradiol.
Aging men sometimes have too much aromatase activity, which causes their testosterone to convert to excess estradiol. This results in depletion of vital testosterone while spiking estradiol to unsafe ranges.
Optimal range: 0.18 - 0.49 ug/g Cr
Estradiol is vital in male health and is measured in the ZRT Laboratory Urinary Neurotransmitters panel. Originating from testosterone, it influences male libido, erectile function, and spermatogenesis. Imbalances can lead to health issues; high estradiol can cause gynecomastia and emotional changes, while low levels may decrease bone density and libido. The ZRT panel helps diagnose hormonal imbalances, assisting healthcare professionals in managing these conditions. Understanding estradiol levels is crucial for treating hormonal issues in males, leading to improved health outcomes.
Optimal range: 0.2 - 1.5 ng/mg Creat/Day
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