AKA: GABA, Gamma-aminobutyric acid, γ-Aminobutyric Acid
- Gamma-aminobutyric acid (GABA) is a chemical that is made in the brain.
- GABA that is made naturally in the brain has anti-seizure and anti-anxiety effects.
- GABA inhibits nerve transmission in the brain, calming nervous activity.
- Gamma-Amino Butyric acid (GABA) is an amino acid which acts as a neurotransmitter in the central nervous system.
- GABA is made in brain cells from glutamate, and functions as an inhibitory neurotransmitter – meaning that it blocks nerve impulses.
References:
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2942977/
- https://www.nytimes.com/2016/11/09/well/mind/breathe-exhale-repeat-the-benefits-of-controlled-breathing.html
- https://www.researchgate.net/publication/11220639_Elevated_plasma_gamma-aminobutyric_acid_GABA_levels_in_autistic_youngsters_Stimulus_for_a_GABA_hypothesis_of_autism
- Low levels in plasma are characteristic of one subset of people with depression. The neurodegenerative condition Huntington's disease, also manifests as lowered levels of GABA as neuron loss proceeds.
- Vitamin B6 deficiency impairs GABA formation, offering one option to help assist people with inadequate GABA production.
- In animal models of seizure, lysine has dose-dependent anticonvulsant effects that appear to be due to GABA receptor modulation.
Understand and improve your laboratory results with our health dashboard.
Upload your lab reports and get interpretation today.
Our technology helps to understand, combine, track, organize, and act on your medical lab test results.
- May reflect decreased ability to convert to succinate for use in the Krebs (citric acid) cycle for energy generation. Cofactors here are α-KG and vitamin B6.
- Gamma-hydroxybutyric aciduria is characteristic of genetic variants with succinic semialdehyde dehydrogenase deficiency. The inevitable retardation of language development in children with this polymorphism is sometimes accompanied by other autistic features. This disorder constitutes one of potential genetic origins of autism.
- Elevated GABA levels, whether primary to illness or compensatory to another process, may be associated with dysfunctional GABAergic neurotransmission in chronic schizophrenia. [L]
Interpret Your Lab Results
Upload your lab report and we’ll interpret and provide you with recomendations today.
Get Started
Get Started With Our Personal Plan
Advanced Plan
Unlimited Plan
Are You a Health Professional?
Get started with our professional plan
Welcome to Healthmatters Pro.
Save time on interpreting lab results with the largest database of biomarkers online. In-depth research on any test at your fingertips, all stored and tracked in one place. Learn more
Pro Plan
for health professionals
$45 per month
At HealthMatters, we're committed to maintaining the security and confidentiality of your personal information. We've put industry-leading security standards in place to help protect against the loss, misuse, or alteration of the information under our control. We use procedural, physical, and electronic security methods designed to prevent unauthorized people from getting access to this information. Our internal code of conduct adds additional privacy protection. All data is backed up multiple times a day and encrypted using SSL certificates. See our Privacy Policy for more details.
1-Methylhistidine (Plasma), 3-Methylhistidine (Plasma), Alanine (Plasma), Alpha-Amino-n-butyric acid (Plasma), Alpha-Aminoadipic Acid (Plasma), Alpha-ANB/Leucine, Anserine (Plasma), Arginine (Plasma), Asparagine (Plasma), Aspartic Acid (Plasma), Beta-Alanine, Beta-Aminoisobutyric Acid (Plasma), Carnosine (Plasma), Citrulline, Cystathionine (Plasma), Cystine, Ethanolamine (Plasma), g-Aminobutyric Acid (Plasma), Glutamic Acid (Plasma), Glutamic Acid/Glutamine, Glutamine (Plasma), Glycine (Plasma), Histidine (Plasma), Homocysteine (Genova), Homocystine (Genova), Hydroxylysine (Genova), Hydroxyproline (Genova), Hydroxyproline/Proline (Genova), Isoleucine (Plasma), Leucine (Plasma), Lysine (Plasma), Methionine (Plasma), Ornithine (Genova), Phenylalanine (Plasma), Phenylalanine/Tyrosine (Genova), Phosphoethanolamine (Plasma), Phosphoserine (Plasma), Proline (Plasma), Sarcosine (Plasma), Serine (Plasma), Taurine (Plasma), Threonine (Plasma), Tryptophan (Plasma), Tryptophan/LNAA (Genova), Tyrosine (Plasma), Valine (Plasma)
