A healthy result should fall into the range 0 - 0.22 Ratio.
Also known as: Alpha-Amino-N-Butyric Acid to Leucine ratio
Alcohol consumption can result in elevations of the plasma Alpha-ANB/Leucine ratio. But to see this biomarker as a conclusive marker for alcoholism is not proven. The increase in the plasma Alpha-ANB/Leucine ratio does not appear to be specific for alcoholism because it was found elevated in nonalcoholic liver disease.
It is most likely that the rise in the plasma Alpha-ANB/Leucine ratio identifies a subgroup of alcoholics. What determines this subgroup of alcoholics remains unclear, but it could be the quantity of alcohol intake, a nutritional deficiency, or the presence of liver disease.
The Alpha-ANB/Leucine ratio can be a marker for alcoholism. Elevations of this amino acid are seen in some alcoholics, but it does not appear to be specific for alcoholism because it was found elevated in nonalcoholic liver disease.
Elevated plasma Alpha-Amino-N-Butyric Acid indicates vitamin B6 insufficiency since this amino acid is metabolized via the usual hepatic transamination reaction requiring pyridoxal phosphate.
In a study the Alpha-ANB/Leucine ratio was also elevated in children with Reye’s syndrome, tyrosinemia, homocystinuria, nonketotic hyperglycinemia, and ornithine transcarbamylase deficiency. The results indicate that an elevated ratio is not specific for adults with alcoholic liver injury and that the ratio may be high even without the presence of clinically apparent hepatic disease. An altered ratio may reflect the presence of an inherent metabolic defect.
$15 per monthSelect this plan
$59 per yearSelect this plan
$250 single paymentSelect this plan
Health is not exactly rocket science. You just have to know what your body needs and doesn't need. Your medical tests contain that information. Upload them to our service and we’ll help you understand organize, and act on them.Get Started
"I was really concerned about my lab results and my GP was not able to see me for another week. Through HealthMatters I was able to interpret my results instantly."
"I've been keeping all my lab results in a spreadsheet, covering approximately 20 years. The HealthMatters team helped me upload that info into the cloud. I can show this data to my family and doctors now easily."
"I had no idea what my lab results meant. Here I found all the biomarkers that I was looking for online. Finally, I have not only organized them all neatly in one place, but I am also grateful to be able to understand what they mean."