Aldosterone is a vital hormone for maintaining proper blood pressure and electrolyte balance. It regulates sodium and potassium levels in the body, ensuring that the correct amount of sodium is retained, and excess potassium is excreted through the kidneys. The synthesis of aldosterone is controlled by the renin-angiotensin system, which activates in response to low blood pressure or high potassium levels. Maintaining optimal aldosterone levels is crucial for overall cardiovascular health and preventing imbalances that can lead to conditions like hypertension, heart disease, or electrolyte disturbances.

Aldosterone is a mineralcoritcoid and a hormone. It allows the transport of sodium across the cell membrane. This is especially important in the kidney (distal tubule). Because of its function, aldosterone is important in blood pressure regulation and also for the volume of blood found in the blood vessels. Potassium is an antagonist to sodium. If potassium is high, sodium levels will be low. When potassium is found high in the plasma of the blood, the adrenals step in and synthesize aldosterone. The synthesis of aldosterone is taken care of in the body primarily by the renin-angiotensin system.

Aldosterone is a mineralcoritcoid and a hormone. It allows the transport of sodium across the cell membrane. Aldosterone is important in blood pressure regulation and also for the volume of blood found in the blood vessels.

The aldosterone-renin ratio (ARR), also known as the aldosterone plasma renin activity (PRA) ratio, is a critical diagnostic tool used in the evaluation of primary aldosteronism, a condition characterized by excessive production of the hormone aldosterone by the adrenal glands.

- Alistipes does not contribute significantly to short chain fatty acid production.

- A diet rich in animal protein and fat increases the abundance of Alistipes.

- High abundance of Alistipes was identified as a possible predictor of successful weight loss.

- Alistipes may positively correlate with depression.

Alistipes does not contribute significantly to short chain fatty acid production. A diet rich in animal protein and fat increases the abundance of Alistipes. High abundance of Alistipes was identified as a possible predictor of successful weight loss. Increased abundance of Alistipes has been correlated with a greater frequency of pain in pediatric irritable bowel syndrome patients.

What is Alkaline phosphatase (ALP)?

Alkaline phosphatase (ALP) is an enzyme (= enzymes are proteins that act as biological catalysts by accelerating chemical reactions) found in the blood that helps break down proteins and that plays a role in numerous processes in the human body. Any abnormalities in blood concentrations (either high or low) may be indicative of diseases ranging from gallstones and thyroid disease to hepatitis and cancer.

ALP is found in all tissues of the body but, not surprisingly, is found in its highest concentration in the liver, bones, kidneys, and intestines as well as the bile ducts (that drain bile from the liver) and gallbladder (that stores bile).

Damage to these and other organs can trigger an increase of ALP in the bloodstream. By contrast, certain diseases or conditions can impair ALP synthesis and lead to a drop in the blood concentration.

Allo-Tetrahydrocorticosterone (5α-THB) is a significant biomarker in dried urine panel analysis, offering vital insights into the body's hormonal balance and stress response. As a metabolite of cortisol, 5α-THB is crucial in understanding the body's glucocorticoid activity, a fundamental aspect of the stress response mechanism. Cortisol, produced by the adrenal glands, is known as the "stress hormone," playing a pivotal role in various physiological processes including metabolism regulation, immune response modulation, and stress adaptation. In the metabolic pathway, cortisol is reduced to tetrahydrocortisol (THF) and subsequently transformed into 5α-THB. This conversion is catalyzed by the enzyme 5α-reductase, which also participates in other critical physiological processes such as androgen metabolism.

Metabolized cortisol is the sum of a-tetrahydrocortisol (a-THF), b-tetrahydrocortisol (b-THF), and b-tetrahydrocortisone (b-THE). They are a good indication of the total cortisol output from the adrenal gland or clearance out the body.

This marker is part of the "17-Hydroxysteroids" group. Please refer to the "17-Hydroxysteroids, Total" marker.

This marker is part of the "17-Hydroxysteroids" group. Please refer to the "17-Hydroxysteroids, Total" marker.

This marker is part of the "17-Hydroxysteroids" group. Please refer to the "17-Hydroxysteroids, Total" marker.

Allo-isoleucine is nearly undetectable in individuals not affected by maple-syrup urine disease (MSUD). Accordingly, its presence is diagnostic for MSUD, and its absence is sufficient to rule-out MSUD.

Allo-isoleucine is nearly undetectable in individuals not affected by maple-syrup urine disease (MSUD). Accordingly, its presence is diagnostic for MSUD, and its absence is sufficient to rule-out MSUD.

Allopregnanediol, or 5a-pregnane-3a,20a-diol, is an endogenous metabolite of progesterone and allopregnanolone and an isomer of pregnanediol.

Allopregnanediol, or 5a-pregnane-3a,20a-diol, is an endogenous metabolite of progesterone and allopregnanolone and an isomer of pregnanediol. Progesterone is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans. It belongs to a group of steroid hormones called the progestogens and is the major progestogen in the body. Progesterone has a variety of important functions in the body. It is also a crucial metabolic intermediate in the production of other endogenous steroids, including the sex hormones and the corticosteroids, and plays an important role in brain function as a neurosteroid. In addition to its role as a natural hormone, progesterone is used as a medication, for instance in menopausal hormone therapy.

Allopregnanolone, also known as brexanolone, is a medication and a naturally produced steroid that acts on the brain. Allopregnanolone possesses a wide variety of effects, including, in no particular order, antidepressant, anxiolytic, stress-reducing, rewarding, prosocial, antiaggressive, prosexual, sedative, pro-sleep, cognitive, memory-impairment, analgesic, anesthetic, anticonvulsant, neuroprotective, and neurogenic effects.

Allopregnanolone is a potent neuroactive steroid capable of binding the GABA-A receptor often leading to sedative and anxiolytic action. The calming action of allopregnanolone is often seen with orally supplemented progesterone, as the liver metabolizes a large portion of oral progesterone to the neuroactive steroid allopregnanolone.

Allopregnanolone, a neurosteroid of growing interest in male health. This metabolite of progesterone plays a crucial role in modulating brain function, particularly influencing mood, stress response, and cognitive processes. In men, allopregnanolone levels are essential for maintaining neurological and psychological well-being. Abnormal levels of allopregnanolone can be indicative of various health issues, ranging from mood disorders to neurodegenerative diseases. The inclusion of allopregnanolone in ZRT's urinary neurotransmitter panel allows for a more comprehensive assessment of a patient's neuroendocrine status, contributing to a deeper understanding of the complex interplay between hormones and neurotransmitters in men's health.