Genova: Complete Hormones (24hr)

Pregnanediol (24hr urine)

A healthy result should fall into the range 0.3 - 4.2 micromol/24 hr.

Progesterone rapidly metabolizes by the time it reaches the urine, and its direct metabolite, pregnanediol, is a reflection of circulating progesterone concentrations.

Progesterone is important for normal reproductive and menstrual function, and influences the health of bone, blood vessels, heart, brain, skin, and many other tissues and organs.

As a precursor, progesterone is used by the body to make other steroid hormones, including DHEA, cortisol, estrogen and testosterone. 

In addition, progesterone plays an important role in mood, blood sugar balance, libido, and thyroid function, as well as adrenal gland health. 

Where is progesterone produced?

Progesterone is primarily produced in the ovaries in premenopausal women and in the adrenal cortex in postmenopausal women. Although progesterone is found in both women and men, the physiological role in men is poorly understood at this point.

Pregnanediol (24hr urine) result calculator

insert the value from you Pregnanediol (24hr urine) test result.

What does it mean if your Pregnanediol (24hr urine) result is too low?

In women, lower levels of progesterone have been associated with dysfunctional uterine bleeding, and may play a role in osteoporosis and impaired neurological function.

The clinical significance of low levels of progesterone in men is poorly understood. Low progesterone levels may be involved in male infertility.

What does it mean if your Pregnanediol (24hr urine) result is too high?

Excessive amounts of progesterone in women can result in problems such as dysglycemia (=a broad term that refers to an abnormality in blood sugar stability), alopecia (=hair loss or baldness), acne, and breast tenderness

The clinical significance of high levels of progesterone in men is poorly understood. Increased levels of progesterone have been found in states of stress and anxiety in men and women: this may relate to its sedative or stress-countering effects. 


Are you concerned about your lab report?
Select your plan, upload your lab reports and we’ll provide you with a meaningful interpretation.

Basic Interpretation
  • Instant interpretation
  • Use self upload form
  • 1000+ biomarkers explained
  • Nutrition Recommendations
  • Cancel anytime
Full Interpretation
  • Instant interpretation
  • We upload 4 reports for you
  • 1000+ biomarkers explained
  • Nutrition Recommendations
  • Cancel anytime
  • Online support
Own It For Life
  • Unlimited access
  • No subscription
  • Instant interpretations
  • We upload 10 reports for you
  • 1000+ biomarkers explained
  • Nutrition Recommendations
  • Dedicated support

Test results don't lie. Learn what is happening inside your body.

Health is not exactly rocket science. You just have to know what your body needs and doesn't need. Your medical tests contain that information. Upload them to our service and we’ll help you understand, organize, and act on them.

Get Started

Medical results explained and interpreted. customer review

"I was really concerned about my lab results and my GP was not able to see me for another week. Through HealthMatters I was able to interpret my results instantly." thankfull female customer

"I've been keeping all my lab results in a spreadsheet, covering approximately 20 years. The HealthMatters team helped me upload that info into the cloud. I can show this data to my family and doctors now easily." thankful young female customer

"I had no idea what my lab results meant. Here I found all the biomarkers that I was looking for online. Finally, I have not only organized them all neatly in one place, but I am also grateful to be able to understand what they mean."

Privacy and security of personal data. HIPAA and GDPR compliant badges.

Your Privacy And Security

At HealthMatters, we're committed to maintaining the security and confidentiality of your personal information. We've put security measures in place to help protect against the loss, misuse or alteration of information under our control. We use procedural, physical and electronic security methods designed to prevent people who aren't authorized from getting access to this information. Our internal code of conduct adds additional privacy protection. See our Privacy Policy for more information.