Optimal Result: 0.6 - 19.9 mcg/g Creat..

Estriol (E3) is considered to be the mildest and briefest-acting of the three estrogens.

Estrogens play a critical role in female sexual development, menstrual function, protein synthesis, cardiovascular function, bone formation and remodeling, cognitive function, emotional balance and other important health factors.

- The estrogenic potency of estradiol (E2) is 12 times that of estrone (E1) and 80 times that of estriol (E3).

- Estradiol (E2) is the primary estrogen in premenopausal women.

- Estrone (E1) is the second most potent estrogen compared to estradiol.

- After menopause, estrone (E1) becomes the primary estrogen as the ovary loses its ability to manufacture estradiol, and it is synthesized in the adrenal glands and fat cells.

Estrogen in men:

Estrogen metabolism and synthesis in men appears to remain relatively stable across the life course.

What does it mean if your Estriol (E3) (24hr) result is too low?

In women, lower levels of estrogens have been associated with a variety of clinical symptoms:

- peri/menopausal symptoms (vasomotor symptoms; mood and memory alterations; diminished skin tone, atrophic vaginitis – a condition associated with decreased vaginal lubrication and thinner vaginal epithelial lining);

- altered lipid metabolism;

- accelerated rate of bone loss.

What does it mean if your Estriol (E3) (24hr) result is too high?

Excessive estrogen levels have been associated with increased risk of some hormonedependent cancers.

In men, low levels of estrogen may be associated with decreased bone density, cognitive decline and cardiovascular disease. Excessive estradiol levels have been associated with greater risk of stroke and cardiovascular disease, as well as BPH, gynecomastia, decreased sexual function and weight gain. Men who have a higher body fat percentage may also have increased estrogen levels, as increased aromatization of testosterone to estradiol can occur in adipose tissue.

Understand blood, stool, and urine medical results from your labs.

10 000+ happy clients
100% satisfaction
★★★★★ customer support

Get 10% off of your first yearly or monthly plan.

Use promocode

Essential Plan


  • Monthly subscription
  • Instant interpretation
  • Use the free self-upload form
  • Additional charge for upload service
  • 2000+ biomarkers explained
  • Recommendations
  • Cancel anytime

Advanced Plan


  • Yearly subscription
  • Instant interpretation
  • We upload five reports for you
  • Use the free self-upload form
  • 2000+ biomarkers explained
  • Nutrition Recommendations
  • Online support
  • Cancel anytime

Own It For Life premium plan


  • No subscription
  • Unlimited access
  • Unlimited storage
  • Instant interpretations
  • We upload ten reports for you
  • Use the free self-upload form
  • 2000+ biomarkers explained
  • Nutrition Recommendations
  • Dedicated support

Healthmatters.io software for professional use.

Welcome to Healthmatters Pro.

Save time on interpreting lab results with the largest database of biomarkers online. In-depth research on any test at your fingertips, all stored and tracked in one place.

Learn More


We implement proven measures to keep your data safe.

At HealthMatters, we're committed to maintaining the security and confidentiality of your personal information. We've put industry-leading security standards in place to help protect against the loss, misuse, or alteration of the information under our control. We use procedural, physical, and electronic security methods designed to prevent unauthorized people from getting access to this information. Our internal code of conduct adds additional privacy protection. All data is backed up multiple times a day and encrypted using SSL certificates. See our Privacy Policy for more details.

General Data Protection Regulation (GDPR). HIPAA compliance for healthcare professionals
×

Understand Your Lab Result Now

  • Instant interpretation
  • 2000+ biomarkers explained
  • Science-based recommendations
  • Online support
  • Secure and private portal

Get 10% off with promocode:

;