Genova: Complete Hormones (24hr)

Etiocholanolone (24hr urine)

Optimal Result: 1.2 - 6.1 micromol/24 hr.

Etiocholanolone is an androstenedione and testosterone metabolite that is excreted in the urine. It is produced from androstenedione and the 5-alpha and 5-beta-reductase metabolic pathways. 

Etiocholanolone levels help the doctor evaluate the performance of bone marrow, and evaluate adrenal cortex function. It’s a 17-ketosterold. In cases of cancer, etiocholanolone may be used for immunostimulation.

The test may also be done when the patient has low DHEA levels, or has low levels of testosterone. Since etiocholanolone is a normal metabolite, if it is found in low levels with test results, then this means that the body is not producing normal levels of androgens.

The enzyme 5-alpha-reductase is responsible for the conversion of testosterone to dihydroestosterone (DHT) that is related to symptoms such as PCOS, acne, hirsutism, male pattern baldness, cancer and enlargement of the prostate. When 5-alpha-reductase activity is high, low levels of etiocholanolone will be found. 

Sources:

  1. https://www.law.cornell.edu/cfr/text/21/862.1285
  2. http://meridianvalleylab.com/wp-content/uploads/2016/06/Urine-Hormone-Interp-Guide.pdf
  3. https://gdx.net/core/interpretive-guides/Urinary-Hormone-Assessment-Interp-Guide.pdf
  4. https://livingwellnessblog.wordpress.com/2013/11/20/hormone-imbalance-autoimmune-disease/ 
  5. https://pubchem.ncbi.nlm.nih.gov/compound/etiocholanolone#section=Top 
  6. Wright, Jonathan, M.D.,; Ellis, Wendy L., N.D.,; and Steriti, Ronald, N.D., Ph.D. 24-Hour Urine Comprehensive Hormone Profile Handbook. page 37. http://tahomaclinic.com/Private/Articles1/LabHandBook.pdf  

What does it mean if your Etiocholanolone (24hr urine) result is too low?

Etiocholanolone levels may be too low in these situations:

- Male hormone insufficiency

- Adrenal insufficiency

- Anorexia nervosa

- Panhypopituitarism

What does it mean if your Etiocholanolone (24hr urine) result is too high?

When etiocholanolone levels are high, the following symptoms may result:

- Inflammation 

- Hot flashes

- Fever

- Increased activity in the white blood cells

- Low levels of iron

- High levels of C-reactive protein

- IL-1 and IL-6 lymphocyte activation

- Autoimmune conditions

Etiocholanolone levels may be high in these situations:

- PCOS (Polycystic Ovarian Syndrome)

- Oversupplementation of DHEA and pregnenalone 

- Androgen producing gonadal tumors

- Adult onset or congenital adrenal hyperplasia

- Serious illness / shock – burns

10 000+ happy clients
100% satisfaction
★ ★ ★ ★ ★ customer support

Understand blood, stool, and urine medical results from all your laboratories.

Get Started With Our Personal Plan

Advanced Plan

  • ✓ Yearly subscription
  • ✓ Five free uploads
  • ✓ Cancel anytime
  • ✓ Instant interpretations
  • ✓ Use the free self-upload form
  • ✓ 3000+ biomarkers explained
  • ✓ Nutrition Recommendations
  • ✓ Dedicated support
  • ✓ Yearly subscription
  • ✓ Five free uploads
  • ✓ Cancel anytime
$79 per year
  • ✓ Instant interpretations
  • ✓ Use the free self-upload form
  • ✓ 3000+ biomarkers explained
  • ✓ Nutrition Recommendations
  • ✓ Dedicated support

Unlimited Plan

  • ✓ No subscription
  • ✓ Ten free uploads
  • ✓ Unlimited access
  • ✓ Instant interpretations
  • ✓ Use the free self-upload form
  • ✓ 3000+ biomarkers explained
  • ✓ Nutrition Recommendations
  • ✓ Dedicated support
  • ✓ No subscription
  • ✓ Ten free uploads
  • ✓ Unlimited access
$250 full version

Are You a Health Professional?

Get started with our professional plan

Welcome to Healthmatters Pro.

Save time on interpreting lab results with the largest database of biomarkers online. In-depth research on any test at your fingertips, all stored and tracked in one place. Learn more

Pro Plan

for health professionals

  • ✓ Track multiple clients results
  • ✓ No setup fees
  • ✓ No hidden costs
  • ✓ Cancel anytime
  • ✓ Instant interpretations
  • ✓ Use the free template forms
  • ✓ 3000+ biomarkers explained
  • ✓ Additional team member $25
  • ✓ Personal training and support

$45 per month

Use promo code to save 10% off any plan.


We implement proven measures to keep your data safe.

At HealthMatters, we're committed to maintaining the security and confidentiality of your personal information. We've put industry-leading security standards in place to help protect against the loss, misuse, or alteration of the information under our control. We use procedural, physical, and electronic security methods designed to prevent unauthorized people from getting access to this information. Our internal code of conduct adds additional privacy protection. All data is backed up multiple times a day and encrypted using SSL certificates. See our Privacy Policy for more details.

×

Understand Your Lab Result Now

  • Instant interpretation
  • 3000+ biomarkers explained
  • Science-based recommendations
  • Online support
  • Secure and private portal

Get 10% off with promocode: