There is evidence that methoxylated estrogens, especially the 2-pathway methoxylated estrogens (E1 and E2), are associated with decreased breast cancer risk; 2-MeOE2, produced from 2-OHE2, has been described to have anti-proliferative, antingiogenic, and pro-apoptotic activity in multiple types of cancer.
A high 2-OH(E1+E2) / 2-MeO(E1+E2) ratio may indicate less methylation activity and/or robust amount of hydroxylated compared to methylated analytes.
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11-Hydroxy-androsterone (24hr urine), 11-Hydroxy-androsterone (FMV urine), 11-Hydroxy-etiocholanolone (24hr urine), 11-Hydroxy-etiocholanolone (FMV urine), 11-Keto-androsterone (24hr urine), 11-Keto-androsterone (FMV urine), 11-Keto-etiocholanolone (24hr urine), 11-Keto-etiocholanolone (FMV urine), 11b-HSD Index (FMV urine), 16a-Hydroxyestrone (16a-OH E1), 16a-Hydroxyestrone (FMV urine), 17-Hydroxysteroids, Total, 17-Hydroxysteroids, Total (24hr urine), 17-Ketosteroids Total (FMV urine), 17-Ketosteroids, Total (24hr urine), 2-Hydroxyestrone (FMV urine), 2-Hydroxyestrone + 2-Hydroxyestradiol [2-OH(E1+E2)], 2-Hydroxyestrone/16a-Hydroxyestrone Ratio (FMV urine), 2-Methoxyestrone (FMV urine), 2-Methoxyestrone+2-Methoxyestradiol [2MeO(E1+E2)], 2-Methoxyestrone/2-Hydroxyestrone Ratio, 2-OH(E1+E2) / 16a-OHE1, 2-OH(E1+E2) / 2-MeO(E1+E2), 4-Hydroxyestrone (FMV urine), 4-Hydroxyestrone+4-Hydroxyestradiol [4-OH(E1+E2)], 4-Methoxyestrone (FMV urine), 4-Methoxyestrone+4-Methoxyestradiol [4MeO(E1+E2)], 5a-Reductase Activity (Etiocholanolone/Androsterone Ratio), allo-Tetrahydrocortisol, a-THF (24hr urine), allo-Tetrahydrocortisol, a-THF (FMV urine), Anabolic/Catabolic Balance (24hr urine), Anabolic/Catabolic Balance (FMV), Androstanediol (24hr urine), Androstanediol (FMV urine), Androsterone (24hr urine), Androsterone (FMV urine), Cortisol, Free (FMV urine), DHEA (24hr urine), DHEA (FMV urine), E/A: 5b/5a Ratio (24hr urine), E/A: 5b/5a Ratio (FMV urine), Estradiol (E2) (24hr), Estradiol (E2) - Premenopause (luteal), Estradiol (FMV urine), Estriol (E3) (24hr), Estriol (E3) - Premenopause (luteal), Estriol (FMV urine), Estrone (E1) (24hr), Estrone (E1) - Premenopause (luteal), Estrone (FMV urine), Etiocholanolone (24hr urine), Etiocholanolone (FMV urine), Pregnanediol (24hr urine), Pregnanediol (FMV urine), Pregnanetriol (24hr urine), Pregnanetriol (FMV urine), Testosterone (24hr urine), Testosterone (FMV urine), Tetrahydrocortisol, THF (24hr urine), Tetrahydrocortisol, THF (FMV urine), Tetrahydrocortisone, THE (24hr urine), Tetrahydrocortisone, THE (FMV urine), Tetrahydrodeoxycortisol (FMV urine), Tetrahydrodeoxycortisol, THS (24hr urine), Triiodothyronine, T3 (FMV urine)