While the traditional 2/16 ratio clinical utility may not be as robust as previously thought, a majority of findings indicate that metabolism of parent estrogens through 2-hydroxylation (independent of any relationship to 16α-OHE1) may be considered as a benign or even protective pathway.
Note: Moderation should be used, however, in up-regulating the "lesser estrogenic" 2- hydroxylation pathway, particularly in women with a positive family history of osteoporosis, since excessive 2-hydroxylation has been associated with decreased bone mineral density
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11-Hydroxy-androsterone (24hr urine), 11-Hydroxy-androsterone (FMV urine), 11-Hydroxy-etiocholanolone (24hr urine), 11-Hydroxy-etiocholanolone (FMV urine), 11-Keto-androsterone (24hr urine), 11-Keto-androsterone (FMV urine), 11-Keto-etiocholanolone (24hr urine), 11-Keto-etiocholanolone (FMV urine), 11b-HSD Index (FMV urine), 16a-Hydroxyestrone (16a-OH E1), 16a-Hydroxyestrone (FMV urine), 17-Hydroxysteroids, Total, 17-Hydroxysteroids, Total (24hr urine), 17-Ketosteroids Total (FMV urine), 17-Ketosteroids, Total (24hr urine), 2-Hydroxyestrone (FMV urine), 2-Hydroxyestrone + 2-Hydroxyestradiol [2-OH(E1+E2)], 2-Hydroxyestrone/16a-Hydroxyestrone Ratio (FMV urine), 2-Methoxyestrone (FMV urine), 2-Methoxyestrone+2-Methoxyestradiol [2MeO(E1+E2)], 2-Methoxyestrone/2-Hydroxyestrone Ratio, 2-OH(E1+E2) / 16a-OHE1, 2-OH(E1+E2) / 2-MeO(E1+E2), 4-Hydroxyestrone (FMV urine), 4-Hydroxyestrone+4-Hydroxyestradiol [4-OH(E1+E2)], 4-Methoxyestrone (FMV urine), 4-Methoxyestrone+4-Methoxyestradiol [4MeO(E1+E2)], 5a-Reductase Activity (Etiocholanolone/Androsterone Ratio), allo-Tetrahydrocortisol, a-THF (24hr urine), allo-Tetrahydrocortisol, a-THF (FMV urine), Anabolic/Catabolic Balance (24hr urine), Anabolic/Catabolic Balance (FMV), Androstanediol (24hr urine), Androstanediol (FMV urine), Androsterone (24hr urine), Androsterone (FMV urine), Cortisol, Free (FMV urine), DHEA (24hr urine), DHEA (FMV urine), E/A: 5b/5a Ratio (24hr urine), E/A: 5b/5a Ratio (FMV urine), Estradiol (E2) (24hr), Estradiol (E2) - Premenopause (luteal), Estriol (E3) (24hr), Estriol (E3) - Premenopause (luteal), Estrone (E1) (24hr), Estrone (E1) - Premenopause (luteal), Etiocholanolone (24hr urine), Etiocholanolone (FMV urine), Pregnanediol (24hr urine), Pregnanediol (FMV urine), Pregnanetriol (24hr urine), Pregnanetriol (FMV urine), Testosterone (24hr urine), Testosterone (FMV urine), Tetrahydrocortisol, THF (24hr urine), Tetrahydrocortisol, THF (FMV urine), Tetrahydrocortisone, THE (24hr urine), Tetrahydrocortisone, THE (FMV urine), Tetrahydrodeoxycortisol (FMV urine), Tetrahydrodeoxycortisol, THS (24hr urine), Triiodothyronine, T3 (FMV urine)
