Lignoceric Acid is a saturated fatty acids, in particular it is part of the group of very long chain fatty acids (VLCFAs).
Accumulation of certain very long chain fatty acids (VLCFAs), such as lignoceric acid, is associated with degenerative diseases of the central nervous system like adrenoleukodystrophy.
There are a number of genetic disorders involving accumulation of sphingolipids, usually due to the lack of enzymes necessary for the turnover of membrane VLCFAs, which include behenic, lignoceric, and hexacosanoic acids as well as the unsaturated members of the C22-24 classes, particularly nervonic acid.
– Kantor, P.F., et al., The antianginal drug trimetazidine shifts cardiac energy metabolism from fatty acid oxidation to glucose oxidation by inhibiting mitochondrial long-chain 3- ketoacyl coenzyme A thiolase. Circ Res, 86(5): p. 580-8 (2000).
– Very Long Chain Fatty Acids Are Functionally Involved in Necroptosis. [L]
Understand and improve your laboratory results with our health dashboard.
Upload your lab reports and get interpretation today.
Our technology helps to understand, combine, track, organize, and act on your medical lab test results.
The common lifestyle of low physical exertion and high fat diet sets a metabolic pattern that can lead to increasing levels of VLCFAs in plasma and erythrocyte membranes. The effect is mediated by hormonal responses, mainly norepinephrine and insulin, and is exacerbated by drugs that modulate energy metabolism such as the anti-anginal drug, trimetazidine.
Interpret Your Lab Results
Upload your lab report and we’ll interpret and provide you with recomendations today.Get Started
Get Started With Our Personal Plan
Are You a Health Professional?
Get started with our professional plan
Welcome to Healthmatters Pro.
Save time on interpreting lab results with the largest database of biomarkers online. In-depth research on any test at your fingertips, all stored and tracked in one place. Learn more
for health professionals
$45 per month
11-Eicosenoic, 25-Hydroxyvitamin D, a-Hydroxybutyric Acid, AA/EPA, Alpha Linolenic, alpha-Tocopherol, Aluminum, Arachidic, Arachidonic, Arsenic, Behenic, Beta-Carotene, Cadmium, Calcium, Capric, Coenzyme Q10 (Genova), Copper, Creatinine, Dihomogamma Linolenic (Genova), Docosadienoic (Genova), Docosahexaenoic (Genova), Docosapentaenoic (Genova), Docosatetraenoic (Genova), Eicosadienoic (Genova), Eicosapentaenoic (Genova), EPA/DGLA (Genova), Gamma Linolenic (Genova), gamma-Tocopherol (Genova), Glyceric Acid, Glycolic, Heneicosanoic (Genova), Heptadecanoic (Genova), Hexacosanoic (Genova), LA/DGLA, Lauric (Genova), Lead (Genova), Lignoceric (Genova), Linoleic (Genova), Lipid Peroxides (Genova), Magnesium (Genova), Mead (Genova), Mercury (Genova), Myristic (Genova), Myristoleic (Genova), Nervonic (Genova), Nonadecanoic (Genova), Oleic (Genova), Oxalic Acid, Palmitelaidic, Palmitic (Genova), Palmitoleic (Genova), Pentadecanoic (Genova), Potassium (Genova), Selenium (Genova), Stearic (Genova), Stearic/Oleic, Total C:18 Trans, Tricosanoic (Genova), Triene/Tetraene (Genova), Vaccenic, Vitamin A (Retinol) (Genova), Zinc (Genova)