The major tissue sites of aluminium toxicity are the nervous system, immune system, bone, liver, and red blood cells. Aluminum may also interfere with heme (porphyrin) synthesis.
Aluminum is used to produce things, such as:
- beverage cans
- cooking pots
- siding
- roofing
- aluminum foil
- airplanes
Further, it is found in:
- antacids
- buffered aspirin
- food additives (especially in grains and cheeses)
- astringents
- vaccinations
- cat litter
- antiperspirants
- infant formula
- baking soda
Aluminum has been detected in calcium, magnesium, and phosphate salts used in parenteral solutions, and it has been found high in lung tissue as a result of tobacco and cannabis smoke inhalation. When aluminum is used in water treatment facilities, concentration in community water supplies can reach 93 µmol/L (2,500 µg/L).
Aluminum and Alzheimer’s disease:
Though not proven as a causative agent, it is striking that the neurofibrillary tangles of neurons that characterize the brains of Alzheimer’s patients (as well as in patients with amyotrophic lateral sclerosis and Parkinson’s and Huntington’s diseases) accumulate aluminum. A study group with aluminum exposure had higher vanilmandelic and homovanillic acids in urine and were significantly different from controls on neurobehavioral tests. As yet no study or group of studies has been able to confirm that aluminium is involved in the development of Alzheimer’s disease.
Aluminum in the body:
Aluminum replaces calcium in bone, disrupting normal osteoid formation and mineralization. Iron deficiency predisposes laboratory animals to higher aluminum absorption and, conversely, aluminum decreases absorption and uptake of iron. Aluminum concentration was found high in the liver and kidney and distribution of essential minerals, in tissues such as bone, brain, liver, and kidney, were altered in aluminum-treated rats.
Copper, zinc, and iron status:
Assessing copper, zinc, and iron status helps to determine vulnerability to the toxic effects of aluminum, and appropriate elemental treatments may help to overcome aluminum toxicity. Testing for anemia is indicated in patients with high RBC, plasma, or serum aluminum. Higher plasma aluminum is seen in infants fed soy formula compared with breast-fed infants.
Serum, erythrocyte, and plasma Aluminum:
Serum, erythrocyte, and plasma aluminum levels appear to correlate. Serum aluminum levels above 5 μmol/L (135 μg/L) are predictive of aluminum toxicity. Testing for anemia is indicated in patients with high blood levels of aluminum.
Hair Aluminum:
High hair aluminum has been shown in aluminum toxicity and therefore, a high value in hair likely reflects a regular source of exposure and should be eliminated.
Urinary Aluminum:
Urinary aluminum can provide information about aluminum intake and has been used to monitor humans exposed to dangerous amounts of aluminum. Because aluminum is ubiquitous in the environment, contamination of a patient’s specimen with aluminum is possible when collection containers are opened in living and work environments.
Desferrioxamine (DFO):
Desferrioxamine (DFO) is a chelator of aluminum and iron that has been used to treat acute aluminum toxicity. In fact, cases of aluminum toxicity are managed similarly to iron toxicity. DFO decreased RBC and plasma aluminum and improved hemoglobin, hematocrit, and mean cell volume in 13 patients. Chelation treatment with desferrioxamine should be handled conservatively due to the risk of inadvertently mobilizing large amounts of aluminum to the brain, which may enhance encephalopathy or a chemical interaction.
DMHP:
The chelator, L1 (1,2-dimethyl-1,3-hydroxypyrid-4-one deferiprone or DMHP) has also been used to lower aluminum total-body burden.
Others:
Ascorbate combined with DFO has been used to remove aluminum from human brain cells. Glycine has been used to help mobilize aluminum.
It is important to assure adequate status of essential elements (calcium, iron, copper, zinc).
Silicon is an antagonist of aluminum.
Further testing:
Further testing of an aluminum-toxicity might involve measurement of bone resorption, urinary catecholamines, oxidative stress, and even vitamin D.
References:
-https://www.alzheimers.org.uk/about-dementia/risk-factors-and-prevention/metals-and-dementia
-https://www.ncbi.nlm.nih.gov/pubmed/8943470
-https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782734/
-https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144270/
-https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691126/
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Consequences of aluminum toxicity are encephalopathy and abnormal speech, myoclonic jerks, convulsions, and a predisposition to osteomalacic fractures. Exposure to aluminum is ubiquitous via food, water, air and soil.
Associated Symptoms and Diseases:
Abnormal speech, myoclonic jerks, osteomalacia, progressive encephalopathy, Alzheimer’s disease, Parkinson’s disease.
Sources:
Aluminum cookware, antacids, drinking water, tobacco, and cannabis smoke.
Protective Measures:
Adequate iron (check ferritin), glycine, calcium, phosphorus (lowers intestinal absorption)
Chelating Agents:
Desferoxamine, DMHP
Possible treatment:
Identify and avoid exposure to the toxic element:
Increase elimination by improving GI, liver, and kidney function:
Protect against damage:
Consider oral or intravenous chelation if warranted by clinical symptoms and test data.
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Anthony
Unlimited Plan Member since 2021
I have been using Healthmatters.io since 2021. I travel all over the world and use different doctors and health facilities. This site has allowed me to consolidate all my various test results over 14 years in one place. And every doctor that I show this to has been impressed. Because with any health professional I talk to, I can pull up historical results in seconds. It is invaluable. Even going back to the same doctor, they usually do not have the historical results from their facility in a graph format. That has been very helpful.
Karin
Advanced Plan Member since 2020
What fantastic service and great, easy-to-follow layouts! I love your website; it makes it so helpful to see patterns in my health data. It's truly a pleasure to use. I only wish the NHS was as organized and quick as Healthmatters.io. You've set a new standard for health tracking!
Paul
Healthmatters Pro Member since 2024
As a PRO member and medical practitioner, Healthmatters.io has been an invaluable tool for tracking my clients' data. The layout is intuitive, making it easy to monitor trends and spot patterns over time. The ability to customize reports and charts helps me present information clearly to my clients, improving communication and outcomes. It's streamlined my workflow, saving me time and providing insights at a glance. Highly recommended for any practitioner looking for a comprehensive and user-friendly solution to track patient labs!
Healthmatters is a highly-personalized health dashboard.
Instead of searching for your lab results in different places or tracking them down from different providers, Healthmatters houses, organizes, and interprets them all in one central location.
With a Healthmatters account, you can dive into the details of each biomarker and gain insights into the meaning behind your medical test data, anytime, anywhere.
For our professional users, Healthmatters provides intuitive tools that not only streamline analysis but also save valuable time when delving into your client's lab report history.
Healthmatters.io personal account provides in-depth research on 4000+ biomarkers, including information and suggestions for test panels such as, but not limited to:
You can combine all test reports inside your Healthmatters account and keep them in one place. It gives you an excellent overview of all your health data. Once you retest, you can add new results and compare them.
If you are still determining whether Healthmatters support your lab results, the rule is that if you can test it, you can upload it to Healthmatters.
While we work with many popular labs, we welcome reports from lots of other places too.
It's as simple as this: if you can get a test done, you can upload it to Healthmatters and we can interpret results from any lab out there. If laboratories can analyze it, we can interpret it.
If you’re on the hunt for a specific biomarker, contact us and we'll add it to our database. Anything from blood, urine, saliva, or stool can be uploaded, understood, and tracked with your Healthmatters account.
There are two ways to add your test reports to your Healthmatters account. One option is to input the data using the data entry forms. The other method is to utilize our "Data entry service."
Our data entry forms offer an easy, fast, and free way for you to input the reports yourself. Self-entry allows you to add an unlimited number of reports at no cost. We make the self-entry process user-friendly, providing dozens of templates that pre-populate the most popular laboratory panels and offering instant feedback on entered values.
For those who prefer assistance, we offer a "Data entry service" to help you input your data. Simply attach an image or file of your lab test results, and a qualified team member from our data entry team will add the results for you.
We support various file types, including PDFs, JPGs, or Excel. This service is particularly useful if you have many reports to upload or if you're too busy to handle the data entry yourself.
Our special data entry service makes it easy to add your results to your private dashboard. Just attach an image or a file of your lab test results, and our skilled data entry team will do the work for you. It's all done by humans, ensuring that your data is entered accurately and with personal care for each client.
Depending on your account, the data entry service can be included for free or come at an additional cost of $15 per report.
For users on the Complete monthly plan, the first report is entered free of charge, and each additional report incurs a fee of $15.
Unlimited account holders enjoy the entry of ten reports without charge. Subsequent reports are subject to a $15 fee per report.
Additionally, users on the Complete plan can upgrade to a yearly subscription from the account settings. The annual subscription includes a data entry service for five reports.
The Unlimited plan is a one-time purchase for $250, and it covers your account for a lifetime with no additional payments.
For the Complete plan, the cost is $15 per month. You have the flexibility to cancel it anytime through your account settings, ensuring no further payments. To avoid charges, remember to cancel at least a day before the renewal date. Once canceled, the subscription remains active until the end of the current billing cycle.
Additionally, you can upgrade to the yearly Advanced plan from within your account. The annual cost is $79, and it comes with a data entry service for five reports.
You can always upgrade to a lifetime version with a prorated price from a monthly or yearly subscription.
Simply log in and navigate to your account settings to cancel your subscription. Scroll down to locate the 'Cancel' button at the bottom of the page. Ensure you cancel at least one day before the renewal date to prevent any charges. Once cancellation is requested, the subscription remains active until the conclusion of the current billing cycle.
Our goal has been to make your Healthmatters account as intuitive as possible.
We’ve crafted multiple ways for you to navigate your data, whether you're glancing at a single report or delving into your historical test reports.
1. Graph View:Dive into a visual journey with our biomarker graphs, showcasing over 40 data points. Combining years of results unveils trends, empowering you to make informed decisions. Our visualization tools make it a breeze to compare and understand changes over time, even if your results are from different labs. A search function and filters simplify the exploration of extensive data, allowing you to focus on what needs attention.
2. All Tests ViewExplore neatly organized reports on a timeline, highlighting crucial details like dates, critical results, and lab/panel names. Each report opens up to reveal in-depth descriptions and additional recommendations for each biomarker. The history of previous results is just a click away, and you can download a comprehensive report for deeper insights. Color-coded and user-friendly, it's designed for easy reading, understanding, and navigation.
3. Table View:For a holistic view of all biomarkers side by side, our table view is your go-to. Results are neatly displayed in a categorized and dated table, ideal for those with an extensive test history. Utilize sorting, filters, and color-coding to enhance your analysis and gain extra insights.
Yes, you can download information from your account. We can compile your labs into a CSV file. To download all your labs, you can go to Account Settings, and at the bottom of the page, you will find a link to download your information.
Yes, you can print your report. To do so, navigate to "All tests" and open the report you wish to print. You'll find a print button in the right corner of the report. Click on it, and your browser's print window will open. If you prefer to print in a bigger typeface, adjust the scale using the print window settings.
Yes, you can! We highly recommend activating Two-Factor Authentication (2FA) for your account. To do so, please navigate to the "Profile and Security" section of your account, where you will find instructions for activating 2FA.
Yes, you can. When entering values for the biomarker, you will see an "Edit Range" button. Click this button, and you'll have the option to enter a custom range.
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To learn more about Healthmatters Pro, please refer to the professional page.
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11-Eicosenoic, 25-Hydroxyvitamin D, a-Hydroxybutyric Acid, AA/EPA, Alpha Linolenic, alpha-Tocopherol, Aluminum, Arachidic, Arachidonic, Arsenic, Behenic, Beta-Carotene, Cadmium, Calcium, Capric, Coenzyme Q10 (Genova), Copper, Creatinine, Dihomogamma Linolenic (Genova), Docosadienoic (Genova), Docosahexaenoic (Genova), Docosapentaenoic (Genova), Docosatetraenoic (Genova), Eicosadienoic (Genova), Eicosapentaenoic (Genova), EPA/DGLA (Genova), Gamma Linolenic (Genova), gamma-Tocopherol (Genova), Glyceric Acid, Glycolic, Heneicosanoic (Genova), Heptadecanoic (Genova), Hexacosanoic (Genova), LA/DGLA, Lauric (Genova), Lead (Genova), Lignoceric (Genova), Linoleic (Genova), Lipid Peroxides (Genova), Magnesium (Genova), Mead (Genova), Mercury (Genova), Myristic (Genova), Myristoleic (Genova), Nervonic (Genova), Nonadecanoic (Genova), Oleic (Genova), Oxalic Acid, Palmitelaidic, Palmitic (Genova), Palmitoleic (Genova), Pentadecanoic (Genova), Potassium (Genova), Selenium (Genova), Stearic (Genova), Stearic/Oleic, Total C:18 Trans, Tricosanoic (Genova), Triene/Tetraene (Genova), Vaccenic, Vitamin A (Retinol) (Genova), Zinc (Genova)
