Genova Diagnostics

Pentadecanoic (Genova)

Optimal Result: 0 - 20.6 µmol/L.

Pentadecanoic acid is an odd numbered fatty acid with a 15-carbon backbone (15:0) and widely considered as one biomarker to assess dairy consumption/intake. It is not normally synthesized by humans, but is found in trace amounts in dairy products (milk fat) and ruminant meat fat.

References:

– https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=NCI_Thesaurus&code=C68413

– https://www.ncbi.nlm.nih.gov/pubmed/25647578

– https://www.ahajournals.org/doi/10.1161/JAHA.113.000393

– https://www.ncbi.nlm.nih.gov/pubmed/14518600?dopt=Abstract

– https://www.ncbi.nlm.nih.gov/pubmed/7644455?dopt=Abstract

– https://www.ncbi.nlm.nih.gov/pubmed/17921367?dopt=Abstract

– https://www.ncbi.nlm.nih.gov/pubmed/22585901?dopt=Abstract

– https://www.ncbi.nlm.nih.gov/pubmed/20089734?dopt=Abstract

– https://www.ncbi.nlm.nih.gov/pubmed/21068345?dopt=Abstract

– https://www.ncbi.nlm.nih.gov/pubmed/21660519?dopt=Abstract

– https://www.ncbi.nlm.nih.gov/pubmed/9925119?dopt=Abstract

– https://www.ncbi.nlm.nih.gov/pubmed/23466047?dopt=Abstract

What does it mean if your Pentadecanoic (Genova) result is too high?

– When measuring fatty acids in whole plasma (not erythrocytes), increased levels of pentadecanoic acid correlate to a more than twofold higher risk of coronary heart disease.

– Pentadecanoic acid is positively correlated with total dairy intake.

– As a possible way to lower penntadecanoic acid level one can reduce overall dairy intake as part of a healthy diet that is rich in fruits, vegetables, and whole grains, but low in sodium, red meats, dairy, sugar sweetened beverages and trans fats.

– Pentadecanoic acid can accumulate in a vitamin B12 deficiency.

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