Arsenic (Genova)

Genova Diagnostics

A healthy result should fall into the range 0 - 13.7 ppb.

Arsenic is a natural component of the earth’s crust and is widely distributed throughout the environment in the airwater and land. It is highly toxic in its inorganic form and considered a carcinogenic heavy metal.

People are exposed to elevated levels of inorganic arsenic through:

  • drinking contaminated water
  • using contaminated water in food preparation
  • irrigation of food crops
  • industrial processes
  • eating contaminated food
  • smoking tobacco

Long-term exposure to inorganic arsenic, mainly through drinking-waterand food, can lead to chronic arsenic poisoning. Skin lesions and skin cancer are the most characteristic effects.

Other specific sources:

  • Rice (Rice accumulates ten times more arsenic than other grains)
  • Rat poisons
  • Automobile exhaust
  • Household detergents
  • Wood preservatives
  • Insecticide residues on fruits and vegetables
  • Wine (if arsenic in pesticides used)
  • Colored chalk
  • Wallpaper dye and plaster
  • Drinking water
  • seawater
  • well water
  • Sewage disposal
  • Seafood (source of nontoxic arsenic)
  • Chicken

Symptoms & effects:

Exposure to arsenic-laden drinking water can induce symptoms of gastroenteritis and lead to cancerdiabetes, and neurological and vascular dysfunction. Long-term arsenic exposure in drinking water shows a dose-response relationship to carotid atherosclerosis. The mechanism involves the induction of expression of genes coding inflammatory mediators.

Arsenic has also been linked to dermatosis and cancers of the skin, bladder, and lung.

Clinical symptoms:

Arsenic exposure is associated with the following clinical symptoms:

  • Neurological: Central depression with visual effects, headache and high fever
  • Hematological: Abnormal RBC counts, increased megalocytes and microcytes
  • GI tract: Increased peristalsis with “rice water” stools
  • Skin: “Milk and roses” complexion from vasodilation, darkening and degeneration

Toxic versus non-toxic and seafood:

Laboratory values of arsenic represent both the toxic form of arsenic and the non-toxic form of arsenic. Because seafood is rich in the non-toxic form of arsenic, the clinician should rule out ingestion of seafood in cases of borderline or moderate arsenic elevation before implementing aggressive therapy.

Urinary arsenic:

Urinary arsenic is most commonly measured to screen for arsenic exposure. Urine reflects arsenic exposure in the few days prior to specimen collection. To eliminate the contribution of seafood to total arsenic levels, avoid seafood 72 hours before test.

Hair, nail and urinary arsenic levels have been shown to be comparable.

Hair/nail arsenic:

Hair or nail arsenic represents several months of exposure prior to taking the specimen. Hair arsenic greater than 1 μg/g dry weight has been taken to indicate excessive exposure.

Serum arsenic:

Since elevated arsenic in the serum drops within 6 to 10 hours, serum is not the best specimen for determining chronic arsenic exposure. Whole blood is suitable for identifying acute exposure to arsenic, and high levels should be addressed immediately.

References:

Arsenic (Genova) result calculator

insert the value from you Arsenic (Genova) test result.

Is your Arsenic (Genova) too high or too low?
Upload your lab report and instantly interpret your result.

DIY Health One

One Lab Report Interpretation

  • One lab report interpretation
  • Use self upload form
  • 800+ biomarkers explained
  • Recommendations
  • Pay per additional interpretations
  • Report uploading support*

15 $

Analyze and Interprete Now

*Additional costs may apply

DIY Health Track

Unlimited Lab Report Interpretations

  • Unlimited lab report interpretations
  • Use self upload form
  • 800+ biomarkers explained
  • Recommendations
  • Online support
  • We do the uploading for you*

59 $/year

Analyze and Interprete Now

*4 report uploads by our team are included per year

Sign Up, Upload Tests, Get Insights and Improve with HealthMatters.io.

Sign up now

Your Privacy And Security

At HealthMatters, we're committed to maintaining the security and confidentiality of your personal information. We've put security measures in place to help protect against the loss, misuse or alteration of information under our control. We use procedural, physical and electronic security methods designed to prevent people who aren't authorized from getting access to this information. Our internal code of conduct adds additional privacy protection. See our Privacy Policy for more information.