AA/EPA (Genova)

Genova Diagnostics

A healthy result should fall into the range 1 - 57 Ratio.

This test measures the ratio of arachidonic acid (AA) to eicosapentaenoic acid (EPA) in plasma. This ratio of the principle omega-3 and omega-6 fatty acids is a measure of the body’s eicosanoid balance. Balancing these eicosanoids in the body is an excellent way
for managing heart disease and other chronic and inflammatory processes.

AA/EPA RANGES CELLULAR INFLAMMATION FUTURE STATE OF WELLNESS
1.5 to 3 Low Excellent
3 to 6 Moderate Good
7 to 15 Elevated Moderate
> than 15 High Poor

Even though cellular or chronic inflammation is silent (absent of pain signals), it can be measured with a number of medical tests.

The AA/EPA Ratio is one of the most common tests for cellular inflammation.

The two other common tests are:

  • hs-C-reactive protein (hs-CRP)
  • Nuclear factor kappa-B (NF-kB)

References:

– https://www.ncbi.nlm.nih.gov/pubmed/17398308

– http://www.clevelandheartlab.com/providers/the-science/

– http://www.clevelandheartlab.com/wp-content/uploads/2018/11/CHL-D003-JUL2018-Artery-Wall-OnePager.pdf

– https://www.medicalnewstoday.com/articles/323144.php

– https://www.nutraingredients-usa.com/Article/2010/11/08/Omega-3-ALA-intakes-enough-for-EPA-DPA-levels-for-non-fish-eaters

– https://epi.grants.cancer.gov/diet/foodsources/fatty_acids/table4.html

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