Our bodies rely on iron in red blood cells to carry oxygen everywhere. Without enough iron, our red blood cells are unable to efficiently supply oxygen. Ferritin is a blood cell protein that holds iron and releases it in controlled intervals. It is produced by every cell in the body, but is found most commonly in the liver, spleen, skeletal muscles, and bone marrow. A ferritin blood test checks the amount of ferritin in the blood, which shows how much iron is stored in your body. A healthcare professional might order a ferritin blood test to:
- Find the cause of anemia, especially iron deficiency anemia
- See if inflammation is present
- See if too much iron is present (hemochromatosis)
- Check if iron treatment to raise or lower the iron level is working
Normal Ranges in ng/mL:
0-1 month: 25-200
1-2 months: 200-600
2-5 months: 50-200
6 months- 14 years: 10-140
Adult male: 24-336
Adult female: 11- 307
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Hemochromatosis, a large buildup of iron in the body, can cause a very high ferritin blood level. In individuals with hereditary hemochromatosis, the daily absorption of iron from the intestines is greater than the amount needed to replace losses. Since the normal body cannot increase iron excretion, the absorbed iron accumulates in the body. The excess iron deposits in the joints, liver, testicles, and heart, which causes damage to these organs and results in signs and symptoms of hemochromatosis. Some other diseases like alcoholism, thalassemia, and some types of anemia that cause red blood cells to be destroyed can also lead to hemochromatosis. High ferritin levels may also be caused by Hodgkin’s disease, leukemia, infection, inflammatory conditions (such as arthritis or lupus), or a diet that is too high in iron.
Symptoms of iron overload may include:
- Joint pain
- Fatigue / weakness
- Weight loss
- Lack of energy
- Abdominal pain
- Loss of sex drive
- Loss of body hair
- Heart problems such as congestive heart failure
For further research on how Ferritin relates to the other markers in an iron panel, please refer to this post:
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Low ferritin levels often mean an iron deficiency is present. This can be caused by chronic blood loss from heavy menstrual bleeding, pregnancy, insufficient iron in the body, or bleeding in the intestinal tract (from ulcers, colon polyps, colon cancer, or hemorrhoids). Another common cause of low blood ferritin is iron deficiency anemia, symptoms include:
- Chronic fatigue / tiredness
- Weakness
- Dizziness
- Headaches
- Pale skin
- Ringing in the ears
- Leg pains
- Shortness of breath
How to increase low ferritin levels:
Doctors treat low ferritin levels with oral iron supplements. For severe cases of anemia, a person may require treatment with intravenous iron. For the best results, people should take oral iron supplements with a source of vitamin C to increase iron absorption. They should avoid antacids, calcium supplements, and tea or coffee within 2 hours of an iron supplement.
If ferritin and blood iron levels do not return to normal following iron supplementation, a doctor may carry out additional testing to determine the cause of the deficiency and treat it accordingly.
For further research on how Ferritin relates to the other markers in an iron panel, please refer to this post:
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11dhTxB2/Creatinine (AspirinWorks), Absolute Reticulocytes, Alpha-1 Antitrypsin Phenotype, Alpha-1-Antitrypsin, Serum, Ammonia, Angiotensin-1-Converting Enzyme, Beta-2 Glycoprotein I Ab, IgA, Beta-2 Glycoprotein I, IgG, Beta-2 Glycoprotein I, IgM, Bicarbonate (HCO3), Serum, C-Reactive Protein (CRP), C-Reactive Protein, Cardiac, Copper, Serum or Plasma, D-Dimer, D-Dimer, Quantitative, Delta Aminolevulinic Acid, Urine, 24 Hour, Erythropoietin (EPO), Serum, F2-Isoprostane, Factor IX Activity, Factor V Leiden Mutation, Factor VII Activity, Factor VIII Activity, Factor X Activity, Factor XI Activity, Ferritin, Ferritin (female range), Fibrinogen Activity, Fibrinogen Antigen, Glucose 6-Phosphate Dehydrogenase (G6PD), Quantitative, Haptoglobin, Hemoglobin A, Hemoglobin F, Immatue Reticulocyte Fraction, Immature Platelet Fraction, Immature Retic Fraction, Iron, IRON (Serum), Lactate Dehydrogenase (LDH or LD), Large Unstained Cells (LUC), Large Unstained Cells (Percent), Macrocytosis, Magnesium, RBC, Nucleated RBC (NRBC) (%), Nucleated red blood cell (NRBC), OxPL-apoB1, Plasminogen Activator Inhibitor 1 (PAI-1) Activity, Platelet Ab, Indirect (IgA), Platelet Ab, Indirect (IgG), Platelet Ab, Indirect (IgM), Plateletcrit (PCT), Polychromasia, Porphobilinogen Deaminase, Whole Blood, Porphyrins, Total Serum, PTT-LA Screen, Retic Hgb Equivalent, Reticulocyte Count, Reticulocyte hemoglobin, Reticulocyte, Absolute, Sickle Cell Screen, Stomatocytes, Thrombin Antithrombin Complex, Thrombocytes, Total iron-binding capacity (TIBC), Transferrin, Transferrin Receptor, Transferrin saturation (Iron Saturation), UIBC
