Blood Health

Factor VII Activity

Optimal Result: 51 - 186 %.

The Factor VII protein is part of the cascade of clotting factors that form the chain leading to a protective blood clot. Factor VII deficiency is usually severe. In fact, patients with less than 1% Factor VII activity experience similar symptoms to hemophilia.

What does it mean if your Factor VII Activity result is too low?

- Congenital factor VII deficiency is rare and is inherited as one of several autosomal recessive mutations.

- Acquired factor VII deficiency is caused by liver disease, vitamin K deficiency or the use of Coumadin (warfarin) therapy.

- Factor VII deficiency is associated with moderate to severe bleeding.

- The combination of a prolonged prothrombin time and normal partial thromboplastin time may indicate factor VII deficiency.

People with severe factor VII deficiency:

- Are prone to joint bleeds

- In addition to spontaneous nosebleeds, people can experience bleeds in the stomach, intestines and urinary tract

- Head bleeds and muscle bleeds have also been reported

- Women can have severe menorrhagia

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