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Optimal range: 2.4 - 15 % of CD19
The marker "Non switched CD27+IgD+IgM+ %" on a Lymphocyte Subset Panel refers to a specific type of cell found within the immune system. This marker is used to identify a subset of B cells, which are crucial components of the immune response. In particular, CD27+IgD+IgM+ denotes B cells that have not undergone a process called class switching. Class switching is a biological mechanism where a B cell changes the type of antibody it produces. However, the cells identified by this marker still produce IgM antibodies, which are among the first types of antibodies generated in response to an infection. These B cells also express CD27, a protein that indicates a certain level of maturity and capability to respond to pathogens. The presence and percentage of these non-switched B cells can provide valuable insights into the body's immune status and its ability to respond to infections or immunological disorders. Therefore, analyzing this marker can help clinicians understand various conditions related to immune function and potentially guide treatment options.
Optimal range: 5 - 46 cells/mcL
Non-switched CD27+IgD+IgM+ Abs are a subset of B cells characterized by the expression of CD27, IgD, and IgM on their surface. These cells are primarily involved in T-cell-independent immune responses and are thought to play a key role in the early defense against pathogens, particularly in mucosal immunity. Unlike class-switched memory B cells, non-switched memory B cells retain IgM as their predominant antibody isotype, enabling rapid responses to previously encountered antigens. Their presence and function are crucial in maintaining immunological memory and have been associated with conditions like autoimmune diseases, chronic infections, and immunodeficiencies. Abnormal levels of these cells may indicate disruptions in immune regulation, prompting further evaluation in clinical and research settings.
Optimal range: 0 - 0.001 %
Non-Crenated Erythrocytes (CSF) refer to red blood cells (RBCs) in cerebrospinal fluid (CSF) that maintain their normal, smooth, biconcave shape. Their presence typically indicates a more recent or acute introduction of blood into the CSF, such as from a traumatic injury, subarachnoid hemorrhage, or traumatic lumbar puncture. Unlike crenated erythrocytes, which form after prolonged exposure to CSF or osmotic stress, non-crenated erythrocytes suggest fresh bleeding or damage. Elevated levels of non-crenated erythrocytes often accompany other markers of acute trauma or hemorrhage and require further evaluation with imaging studies and additional CSF analysis to identify the source and extent of the underlying issue.
Optimal range: 0 - 1.8 ELISA Index
Alpha-amylase and serpin can escape digestion and activate toll-like receptor-4 (TLR4). Immune reactivity and clinical manifestations of non-gluten proteins are most often associated with hypersensitivities/allergies. IgG and IgA antibodies to non-gluten proteins may be present due to cross-reactivity between non-gluten and gluten proteins. Homology between g-gliadin and non-gluten proteins has been shown. Furthermore, wheat, barley, rye and corn belong to the same family of a-amylase inhibitors.
Optimal range: 0 - 1.3 ELISA Index
LEARN MOREOptimal range: 0.3 - 1.3 ELISA Index
LEARN MOREOptimal range: 0 - 3 ELISA Index
The "Non-Gluten Proteins-B IgG" marker is designed to detect immune system reactions to a variety of proteins in wheat that are not classified as gluten. While gluten often gets the most attention due to its association with celiac disease and gluten sensitivity, wheat contains a broad array of other proteins that can also trigger immune responses in some individuals. These non-gluten proteins can provoke IgG antibodies, which are a type of antibody that the immune system produces in response to what it perceives as foreign invaders.
Optimal range: 0 - 4 mmol/L
Your non-HDL cholesterol result refers to your total cholesterol value minus your HDL cholesterol. Your lipid panel results normally include four numbers:
- low-density lipoprotein (LDL) cholesterol;
- high-density lipoprotein (HDL) cholesterol;
- triglycerides; and
- total cholesterol.
Optimal range: 0 - 130 mg/dL , 0.00 - 3.37 mmol/L
Your non-HDL cholesterol result refers to your total cholesterol value minus your HDL cholesterol. Your lipid panel results normally include four numbers:
- low-density lipoprotein (LDL) cholesterol;
- high-density lipoprotein (HDL) cholesterol;
- triglycerides; and
- total cholesterol.
Optimal range: 0 - 1.89 µmol/L
Nonadecanoic Acid is an odd chain fatty acid.
Fatty acids with odd numbers of carbon atoms are produced primarily by initiating the synthetic series with the three carbon compound, propionic acid.
Optimal range: 0.07 - 0.88 mmol/L
Nonesterified Fatty Acids (NEFAs), also known as Free Fatty Acids (FFAs), are a type of fatty acid that circulate in the bloodstream without being attached to a glycerol molecule. They play a crucial role in energy metabolism, serving as a major energy source during fasting or periods of increased energy demand.
NEFAs can be derived from the breakdown of stored triglycerides in adipose tissue, and they are also released in response to various physiological conditions, including stress, exercise, and fasting.
Optimal range: 30 - 50 ug/g Cr
Norepinephrine, also known as noradrenaline, is important for mental focus and emotional stability.
Norepinephrine functions as a neurotransmitter and hormone that regulates the “fight or flight” response and elevates blood pressure and heart rate, stimulates wakefulness, and reduces digestive activity.
Optimal range: 20 - 108 mcg/g Cr
Norepinephrine is one of the catecholamines measured in the Catecholamines, Fractionated, Random Urine test.
Norepinephrine, also known as noradrenaline, is a hormone and neurotransmitter produced by the adrenal glands, as well as certain nerve cells (neurons) in the sympathetic nervous system. It plays a crucial role in the body's "fight or flight" response, helping to prepare the body for action by increasing heart rate, constricting blood vessels, and raising blood pressure.
Optimal range: 22 - 50 µg/g
Norepinephrine, also called noradrenaline, is an excitatory neurotransmitter produced in the CNS, as well as a stress hormone produced in the adrenal medulla. Norepinephrine is involved in a wide variety of actions including attention, focus, regulating heart rate, affecting blood flow, and suppressing inflammation. Involved in arousal, it prepares the body for action by relaying messages in the sympathetic nervous system as part of the autonomic nervous system’s fight-or-flight response.
Optimal range: 217 - 1109 pg/mL
Norepinephrine (also called noradrenaline) is one of the catecholamines. Catecholamines are hormones made by the adrenal glands. The three catecholamines are epinephrine (adrenalin), norepinephrine, and dopamine.