Diethylphosphate (DEP) is a metabolite of organophosphate pesticides, which are commonly used in agriculture to control pests and in residential environments to manage insects and rodents. Organophosphates exert their effects by inhibiting acetylcholinesterase, an enzyme crucial for proper nerve function. This inhibition disrupts nerve signaling, which can lead to a range of health issues.

Exposure to organophosphate pesticides, and consequently to DEP, has been associated with several health concerns, including neurological deficits, neurodegenerative diseases, and peripheral nerve damage. Furthermore, long-term exposure may contribute to neurodevelopmental issues, oxidative stress, psychological effects, and liver function abnormalities.

Monitoring DEP levels through panels like ToxDetect helps assess exposure to organophosphates and their potential impacts on health. Understanding DEP concentrations can guide preventive measures to reduce the risks associated with these toxic chemicals.

Organophosphates are one of the most toxic groups of substances in the world, primarily found in pesticide formulations. They are inhibitors of cholinesterase enzymes, leading to overstimulation of nerve cells, causing sweating, salivation, diarrhea, abnormal behavior, including aggression and depression. Children exposed to organophosphates have more than twice the risk of developing pervasive developmental disorder (PDD), an autism spectrum disorder. Maternal organophosphate exposure has been associated with various adverse outcomes including having shorter pregnancies and children with impaired reflexes.

Dihomogamma Linolenic Acid (DGLA) is the elongation product of Gamma-linolenic acid (GLA).

Dihomo-gamma-linolenic acid (DGLA) is a fatty acid and part of the Omega-6 fatty acids family. Those fatty acids can predominatentely be found in vegetable oils, grains, most meats and dairy. 

DGLA is a strong anti-inflammatory.

Dihomo-gamma-linolenic acid (DGLA) is a 20-carbon omega-6 with 3 double bonds (20:3n6) derived from the essential linolenic acid. LA is metabolized to GLA, which is rapidly elongated to DGLA. There are only trace amounts of DGLA found in organ meats, otherwise it must be synthesized from GLA. The inability to convert precursor fatty acids to DGLA is associated with various pathologic and physiologic conditions such as aging, diabetes, alcoholism, atopic dermatitis, rheumatoid arthritis, cancer, and cardiovascular disease.

Dihomogamma Linolenic Acid (DGLA) is the elongation product of Gamma-linolenic acid (GLA).

Dihomo-gamma-linolenic acid (DGLA) is a fatty acid and part of the Omega-6 fatty acids family. Those fatty acids can predominatentely be found in vegetable oils, grains, most meats and dairy. 

DGLA is a strong anti-inflammatory.

Dihomogamma Linolenic Acid (DGLA) is the elongation product of Gamma-linolenic acid (GLA).

Dihomo-gamma-linolenic acid (DGLA) is a fatty acid and part of the Omega-6 fatty acids family. Those fatty acids can predominatentely be found in vegetable oils, grains, most meats and dairy. 

DGLA is a strong anti-inflammatory.

Dihydrocitrinone (DHC) is a metabolite of Citrinin (CTN), which is a mycotoxin produced by several fungal strains in the Penicillium, Aspergillus and Monascus genera and found in stored grains and other food products. Citrinin has nephrotoxic and genotoxic effects, and often occurs in combination with ochratoxin A. Studies show that dihydrocitrinone (DHC) has a signicantly reduced cytotoxic and genotoxic potential as compared to CTN. Thus, DHC is considered a detoxication related step of CIT metabolism.

Dihydrocitrinone is a metabolite of Citrinin (CTN), which is a mycotoxin that is produced by mold species of the genera Aspergillus, Penicillium, and Monascus. 

CTN exposure can lead to nephropathy, because of its ability to increase permeability of mitochondrial membranes in the kidneys. The three most common exposure routes are through ingestion, inhalation, and skin contact.

CTN has been shown to be carcinogenic in rat studies. Multiple studies have linked CTN exposure to a suppression of the immune response. 

Dihydrotestosterone (DHT) is a key androgenic marker providing critical insights into androgen metabolism and its implications in female health. DHT, a biologically active metabolite of testosterone, is formed primarily in peripheral tissues through the action of the enzyme 5-alpha-reductase. Despite being commonly associated with male physiology, DHT plays a significant role in women, particularly in hair follicle health, skin condition, and overall hormonal balance. Elevated levels of DHT in women can lead to androgenic effects such as hirsutism (excessive hair growth in areas typical for males), acne, and in some cases, androgenic alopecia (pattern hair loss). These symptoms are often observed in conditions like polycystic ovary syndrome (PCOS), which is characterized by an overproduction of androgens.

Dihydrotestosterone (DHT) is a potent androgen—a type of sex hormone—that plays a key role in the development of male sexual characteristics. It is primarily active during fetal development and puberty in individuals assigned male at birth, and it contributes to traits like body hair, prostate growth, and male-pattern baldness. While DHT is present in people of all sexes, its role is more prominent in male reproductive physiology.

Dihydrotestosterone is a hormone that stimulates the development of male characteristics

HVA and DOPAC are the major metabolites of dopamine.

HVA and DOPAC are the major metabolites of dopamine.

HVA and DOPAC are the major metabolites of dopamine.

HVA and DOPAC are the major metabolites of dopamine.

Produced when Clostridia acts upon unabsorbed tryptophan, tyrosine or phenylalanine.

Dihydroxyphenylpropionic Acid (DHPPA), also known as 3,4 dihydroxyphenylpropionic acid, is a byproduct of the fermentation of dietary phenols by several bacteria, including some Clostridia spp. and others. Although once thought to identify the presence of specific dysbiotic bacteria, ongoing research suggests there are several bacterial species potentially involved.