What is a chloride blood test?
A chloride blood test (serum chloride) measures the level of chloride in your blood. Chloride is one of the electrolytes in your blood. Electrolytes are minerals that carry an electric charge when they are dissolved in a liquid. The electrolytes in your blood — chloride, sodium, potassium and bicarbonate — help control nerve and muscle function and maintain the acid-base balance (pH balance) of your blood and your water balance. The amount of chloride in your blood is often measured along with other electrolytes to diagnose or monitor certain medical conditions, including:
- Kidney disease.
- Heart failure.
- Liver disease.
- High blood pressure.
- What is a chloride blood test used for?
Healthcare providers usually don’t order individual chloride blood tests. Chloride blood tests are usually included in the following routine blood tests and screenings that measure multiple things in your blood:
- Comprehensive metabolic panel (CMP).
- Basic metabolic panel (BMP).
- Electrolyte panel.
The results of a chloride blood test, alongside the results of other electrolyte tests, can help diagnose a condition related to an imbalance of acids or fluids in your body.
Why do I need a chloride blood test?
Your healthcare provider may have ordered a chloride blood test as part of a routine blood panel. Your healthcare provider may also order a chloride blood test if you have symptoms of an acid or fluid imbalance, including:
- Experiencing multiple instances of vomiting.
- Having diarrhea.
- Feeling very tired (fatigue).
- Feeling weak.
- Experiencing dehydration.
- Having difficulty breathing (respiratory distress).
What is a normal chloride blood test result?
A typical normal range for a chloride blood test for an adult is 96 to 106 milliequivalents per liter (mEq/L) or 96 to 106 millimoles per liter. However, laboratories may have different reference ranges for normal chloride levels. When you get your blood test results back, there will be information that indicates what that lab’s normal blood chloride range is. If you have any questions about your results, be sure to ask your healthcare provider.
Sources:
- Chloride Test -- https://www.testing.com/tests/chloride/
- Health Encyclopedia, Chloride -- https://www.urmc.rochester.edu/encyclopedia/content.aspx?ContentTypeID=167&ContentID=chloride
- Blood Tests -- https://www.nhlbi.nih.gov/health/blood-tests
- MedlinePlus. Chloride Blood Test -- https://medlineplus.gov/lab-tests/chloride-blood-test
- Merck Manual Consumer Version. Overview of Electrolytes -- https://www.merckmanuals.com/home/hormonal-and-metabolic-disorders/electrolyte-balance/overview-of-electrolytes
References:
American Board of Internal Medicine. ABIM Laboratory Test Reference Ranges -- https://www.abim.org/Media/bfijryql/laboratory-reference-ranges.pdf
Lewis JL III. Overview of Electrolytes. Merck Manual Consumer Edition -- https://www.merckmanuals.com/home/hormonal-and-metabolic-disorders/electrolyte-balance/overview-of-electrolytes
A.D.A.M. Medical Encyclopedia. Chloride Test – Blood -- https://medlineplus.gov/ency/article/003485.htm
Hinkle J, Cheever K. Brunner & Suddarth's Handbook of Laboratory and Diagnostic Tests. 2nd Ed, Kindle. Philadelphia: Wolters Kluwer Health, Lippincott Williams & Wilkins; c2014. Chloride, Serum; p. 153–4.
Merck Manual Consumer Version: Merck & Co. Inc.; c2022. Acidosis -- https://www.merckmanuals.com/home/hormonal-and-metabolic-disorders/acid-base-balance/acidosis
Merck Manual Consumer Version: Merck & Co. Inc.; c2022. Addison Disease (Addison's Disease; Primary or Chronic Adrenocortical Insufficiency) -- https://www.merckmanuals.com/home/hormonal-and-metabolic-disorders/adrenal-gland-disorders/addison-disease
Merck Manual Consumer Version: Merck & Co Inc.; c2022. Acidosis -- https://www.merckmanuals.com/home/hormonal-and-metabolic-disorders/acid-base-balance/acidosis
Merck Manual Consumer Version: Merck & Co. Inc.; c2022. Overview of Acid-Base Balance -- https://www.merckmanuals.com/home/hormonal-and-metabolic-disorders/acid-base-balance/overview-of-acid-base-balance
Merck Manual Professional Version: Merck & Co. Inc.; c2022. Acid-Base Disorders -- http://www.merckmanuals.com/professional/endocrine-and-metabolic-disorders/acid-base-regulation-and-disorders/acid-base-disorders
National Heart, Lung, and Blood Institute: U.S. Department of Health and Human Services; Blood Tests -- http://www.nhlbi.nih.gov/health-topics/blood-tests
Adrogué HJ, Madias NE. Respiratory acidosis, respiratory alkalosis, and mixed disorders. In: Feehally J, Floege J, Tonelli M, Johnson RJ, eds. Comprehensive Clinical Nephrology. 6th ed. Philadelphia, PA: Elsevier; 2019:chap 14.
Giavarina D. Blood biochemistry: measuring major plasma electrolytes. In: Ronco C, Bellomo R, Kellum JA, Ricci Z, eds. Critical Care Nephrology. 3rd ed. Philadelphia, PA: Elsevier; 2019:chap 54.
Seifter JR. Acid-base disorders. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 110.
What does a high chloride level mean?
If your results reveal that you have higher-than-normal levels of chloride in your blood, it may indicate that you have:
- Dehydration.
- Kidney disease.
- Cushing’s syndrome.
- Metabolic acidosis (having too much acid in your blood, or a lower-than-normal blood pH).
- Respiratory alkalosis (having a low level of carbon dioxide in your blood due to breathing excessively, or hyperventilating).
An increased level of blood chloride is typically caused by dehydration but may also occur with problems that cause high blood sodium (such as Cushing syndrome or kidney disease). A high amount of chloride also occurs when too much base is lost from the body (causing metabolic acidosis) or when a person hyperventilates (causing respiratory alkalosis).
It’s important to remember that a high chloride result doesn’t necessarily mean that you have a medical condition. Certain situations and medications can also increase your chloride levels.
To lower chloride levels in the blood, it is crucial to address the underlying cause. Here are some general strategies that might help:
→ Dietary modifications: Avoiding high-chloride foods like table salt and processed foods can be beneficial.
→ Hydration: Increasing water intake can dilute chloride levels in the blood.
→ Medication adjustment: Consult a healthcare professional to assess any medications that might be contributing to high chloride levels.
The most effective approach would depend on the specific cause of elevated chloride levels. Consulting a healthcare provider for personalized guidance and treatment is crucial.
Import lab results from multiple providers, track changes over time, customize your reference ranges, and get clear explanations for each result. Everything is stored securely, exportable in one organized file, and shareable with your doctor—or anyone you choose.
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Chloride is an essential electrolyte that helps maintain your body’s acid-base balance, fluid levels, and electrical neutrality in cells. It works closely with sodium, potassium, and bicarbonate to regulate hydration and pH. Serum chloride levels are routinely measured as part of a Comprehensive Metabolic Panel (CMP)—even when the test is done without fasting.
A low chloride level in the blood is called hypochloremia. It can reflect fluid imbalances, acid-base disturbances, or be a secondary effect of various underlying medical conditions or medications.
Loss of stomach contents (which are rich in hydrochloric acid) leads to a loss of chloride and hydrogen ions, resulting in metabolic alkalosis.
Conditions such as chronic obstructive pulmonary disease (COPD) can cause chronic CO2 retention, leading to compensatory metabolic alkalosis with low chloride.
Loop diuretics and thiazide diuretics (commonly prescribed for high blood pressure or heart failure) increase urinary loss of chloride, sodium, and potassium.
Excessive intake of free water (or conditions like SIADH, Syndrome of Inappropriate Antidiuretic Hormone Secretion) can dilute blood chloride levels.
Both conditions may cause fluid retention and dilutional hyponatremia, often accompanied by low chloride.
Low chloride levels often appear alongside high bicarbonate levels, reflecting a shift in acid-base balance.
While mild cases may have no symptoms, moderate to severe hypochloremia can cause:
Muscle twitching or weakness
Dehydration
Fatigue
Difficulty breathing (if associated with acid-base disturbances)
Confusion or irritability (in severe cases)
A Comprehensive Metabolic Panel (CMP) includes chloride along with sodium, potassium, CO2 (bicarbonate), and other metabolic markers. Low chloride is often evaluated alongside:
Sodium and bicarbonate levels
Kidney function markers (creatinine, BUN)
Arterial blood gases (ABG) in complex cases
A single low chloride result—especially from a non-fasting test—should be interpreted in the context of:
Hydration status
Medications (especially diuretics)
Recent illness (vomiting, diarrhea, infections)
Other lab values on the CMP
Your healthcare provider may:
Review your medications
Order follow-up electrolyte tests or blood gas analysis
Recommend adjustments to your diet or fluid intake
Address any underlying conditions such as kidney disease, heart failure, or acid-base imbalance
A decreased serum chloride level on a non-fasting Comprehensive Metabolic Panel may suggest an electrolyte imbalance, often due to vomiting, diuretic use, chronic respiratory illness, or metabolic alkalosis. While not always a cause for concern, persistently low levels may require further evaluation and treatment depending on the underlying cause.
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Easily upload lab results from any provider, whether it's a hospital, independent lab, or home testing service. We support PDFs, scanned documents, and JPEGs from patient portals. No need to log in to multiple platforms — everything is centralized in one secure space.
Easily upload lab results from any provider — we support PDFs, scans, and images. Keep all your reports organized in one secure place.
Every lab result is automatically organized on a chronological timeline, giving you a complete picture of your health journey. Whether you're tracking a condition, managing treatments, or staying proactive, the timeline helps you and your doctor understand how things progress over time.
Every lab result is automatically organized on a chronological timeline, giving you a complete picture of your health journey.
Whether it's a blood test, GI panel, urinalysis, or something else, lab reports measure numerous biomarkers that reveal what's happening inside your body. Our extensive database covers over 10,000 biomarkers, providing clear, simple explanations of what each result means and how you can take action—no matter your membership level. Say goodbye to confusion and get the insights you need to better understand your health.
Our database covers over 10,000 biomarkers with clear, simple explanations—so you can finally understand your results and what to do next.
If you'd like to handle inputting your health data into your account, you can do so with our easy-to-use data entry forms. Our user-friendly form is designed to guide you through the quick and easy submission process, making it simple to keep track of your health metrics. This is available to both Complete plan and Unlimited plan members.
Our user-friendly form guides you through a quick, simple submission process, making it easy to enter your health metrics.
Add your results anytime with our easy entry form. It's quick, guided, and helps you stay organized — free for all members.
View your lab data through easy-to-read graphs and tables. Quickly spot patterns, track changes, and compare results across different dates — all without digging through multiple reports. You can also select and compare graphs of specific biomarkers side-by-side to better understand how they relate and change over time.
See your lab reports in clear graphs and tables. Spot patterns, track changes, and compare results over time — all in one place.
After collecting lab results from different providers, you can download your entire history combined into a single file. Choose from PDF, Excel, or CSV formats to easily review, share, or get a second opinion—no more juggling multiple reports.
After collecting lab results from different providers, you can download your entire history combined into a single file.
Our inclusive service handles the data entry for your lab reports. Just submit your information and we'll take care of the rest. Complete plan members receive one report entered for free, then $15 per report after that. Unlimited plan members receive ten report entries for free, then $15 per report after that.
Our inclusive service handles the data entry for your lab reports. Just submit your information and we'll take care of the rest.
Whether you're working with a doctor, nutritionist, caregiver, or wellness coach, you can securely share your complete lab history by sending an invite link to anyone you trust. You have full control over who sees your information and for how long, ensuring your privacy and peace of mind at every step.
Share your full lab history with your doctor, nutritionist, or coach using a secure invite link.
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I have been using Healthmatters.io since 2021. I travel all over the world and use different doctors and health facilities. This site has allowed me to consolidate all my various test results over 14 years in one place. And every doctor that I show this to has been impressed. Because with any health professional I talk to, I can pull up historical results in seconds. It is invaluable. Even going back to the same doctor, they usually do not have the historical results from their facility in a graph format. That has been very helpful.
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As a PRO member and medical practitioner, Healthmatters.io has been an invaluable tool for tracking my clients' data. The layout is intuitive, making it easy to monitor trends and spot patterns over time. The ability to customize reports and charts helps me present information clearly to my clients, improving communication and outcomes. It's streamlined my workflow, saving me time and providing insights at a glance. Highly recommended for any practitioner looking for a comprehensive and user-friendly solution to track patient labs!
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Healthmatters is a personal health dashboard that helps you organize and understand your lab results. It collects and displays your medical test data from any lab in one secure, easy-to-use platform.
With a Healthmatters account, you can:
Professionals can also analyze client data more efficiently and save time managing lab reports.
Healthmatters.io personal account provides in-depth research on 4000+ biomarkers, including information and suggestions for test panels such as, but not limited to:
You can combine all test reports inside your Healthmatters account and keep them in one place. It gives you an excellent overview of all your health data. Once you retest, you can add new results and compare them.
If you are still determining whether Healthmatters support your lab results, the rule is that if you can test it, you can upload it to Healthmatters.
While we work with many popular labs, we welcome reports from lots of other places too.
It's as simple as this: if you can get a test done, you can upload it to Healthmatters and we can interpret results from any lab out there. If laboratories can analyze it, we can interpret it.
If you're on the hunt for a specific biomarker, contact us and we'll add it to our database. Anything from blood, urine, saliva, or stool can be uploaded, understood, and tracked with your Healthmatters account.
The Complete Plan ($15/month) is perfect for individuals who want ongoing access to their health data. It includes unlimited lab imports, visual tracking, custom ranges, result explanations, full account exports, and secure sharing — all with a simple monthly subscription. You can cancel anytime and restart your plan whenever you're ready — your data will still be there waiting for you. You can also upgrade to the Unlimited Plan at any time, with the cost prorated based on what you've already paid.
The Unlimited Plan ($250 one-time) is also designed for individuals but offers lifetime access with no ongoing subscription. You'll get all the same features as the Complete Plan, plus a larger initial data entry allowance (10 reports), making it a great choice if you prefer a one-time payment and long-term use without monthly fees.
In short:
There are two ways to add your test reports to your Healthmatters account. One option is to input the data using the data entry forms. The other method is to utilize our "Data entry service."
Our data entry forms offer an easy, fast, and free way for you to input the reports yourself. Self-entry allows you to add an unlimited number of reports at no cost. We make the self-entry process user-friendly, providing dozens of templates that pre-populate the most popular laboratory panels and offering instant feedback on entered values.
For those who prefer assistance, we offer a "Data entry service" to help you input your data. Simply attach an image or file of your lab test results, and a qualified team member from our data entry team will add the results for you.
We support various file types, including PDFs, JPGs, or Excel. This service is particularly useful if you have many reports to upload or if you're too busy to handle the data entry yourself.
Our Data Entry Service is for when you don't want to manually type in your lab results yourself. You simply upload your report (PDF, image, or screenshot), and our trained team enters the information into your Healthmatters account for you — accurately and neatly organized, ready to view in graphs, tables, and timelines.
The $15 per report covers the time and care it takes for a real person to review your file, make sure each result is entered correctly, and double-check for accuracy. This ensures your health data is precise and easy to work with — without you having to spend the time doing it yourself.
Prefer to do it yourself? You can always use our free self-entry tool to add results manually — it just takes a bit more time and attention.
For users on the Complete monthly plan, the first report is entered free of charge, and each additional report incurs a fee of $15.
Unlimited account holders enjoy the entry of ten reports without charge. Subsequent reports are subject to a $15 fee per report.
Additionally, users on the Complete plan can upgrade to a yearly subscription from the account settings. The annual subscription includes a data entry service for five reports.
All professional accounts allow you to import and onboard an unlimited number of clients and their lab results. The distinction between professional plans lies solely in the data entry service.
The Pro Monthly Plus plan is priced at $75 per month and includes a data entry service for five reports each month. Additional reports can be self-entered at no extra cost or, if preferred, you can use our data entry service for an additional fee of $15 per report.
The Pro Monthly plan is priced at $45 per month and does not include a data entry service. Self-entry is free for an unlimited number of reports, and you can opt for the data entry service at a fee of $15 per report.
You also have the option to upgrade to higher monthly or to annual plans, which come with substantial discounts. All upgrades can be done directly from your account.
Simply log in and navigate to your account settings to cancel your subscription. Scroll down to locate the 'Cancel' button at the bottom of the page. Ensure you cancel at least one day before the renewal date to prevent any charges. Once cancellation is requested, the subscription remains active until the conclusion of the current billing cycle.
Our goal has been to make your Healthmatters account as intuitive as possible.
We've crafted multiple ways for you to navigate your data, whether you're glancing at a single report or delving into your historical test reports.
1. Graph View:Dive into a visual journey with our biomarker graphs, showcasing over 40 data points. Combining years of results unveils trends, empowering you to make informed decisions. Our visualization tools make it a breeze to compare and understand changes over time, even if your results are from different labs. A search function and filters simplify the exploration of extensive data, allowing you to focus on what needs attention.
2. All Tests ViewExplore neatly organized reports on a timeline, highlighting crucial details like dates, critical results, and lab/panel names. Each report opens up to reveal in-depth descriptions and additional recommendations for each biomarker. The history of previous results is just a click away, and you can download a comprehensive report for deeper insights. Color-coded and user-friendly, it's designed for easy reading, understanding, and navigation.
3. Table View:For a holistic view of all biomarkers side by side, our table view is your go-to. Results are neatly displayed in a categorized and dated table, ideal for those with an extensive test history. Utilize sorting, filters, and color-coding to enhance your analysis and gain extra insights.
Yes, you can download your information anytime. We offer two easy ways to export your lab data:
This makes it simple to save, back up, or share your health data whenever you need.
Yes, you can print your report. To do so, navigate to "All tests" and open the report you wish to print. You'll find a print button in the right corner of the report. Click on it, and your browser's print window will open. If you prefer to print in a bigger typeface, adjust the scale using the print window settings.
Yes, you can! We highly recommend activating Two-Factor Authentication (2FA) for your account. To do so, please navigate to the "Profile and Security" section of your account, where you will find instructions for activating 2FA.
Yes, you can. When entering values for the biomarker, you will see an "Edit Range" button. Click this button, and you'll have the option to enter a custom range.
A personal account is all about keeping your own lab test results in check. It's just for you and your personal use.
The professional account is designed for health professionals who wish to track and organize their clients' laboratory results.
To learn more about Healthmatters Pro, please refer to the professional page.
At HealthMatters, we're committed to maintaining the security and confidentiality of your personal information. We've put industry-leading security standards in place to help protect against the loss, misuse, or alteration of the information under our control. We use procedural, physical, and electronic security methods designed to prevent unauthorized people from getting access to this information. Our internal code of conduct adds additional privacy protection. All data is backed up multiple times a day and encrypted using SSL certificates. See our Privacy Policy for more details.